接受或拒绝脐带血单位的标准

IF 1.1 Q4 ALLERGY
Khalid Kazim
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引用次数: 0

摘要

罕见的造血干细胞群负责移植植入过程。脐带血(UCB)通常被加工成总有核细胞(TNC),而不是单核细胞(MNC)部分。TNC计数用于确定UCB单位储存、移植释放以及与植入时间[1]的相关性。文献中提到,有几个因素会影响脐带血干细胞的采集。本研究旨在分析胎儿体重与其他因素之间的关系,这些因素导致了来自公共和私人捐赠的CBUs对DCRC的排斥反应。在本回顾性研究中,记录了2018年1月至2018年10月DCRC的375例CBUs捐赠。从文献中,记录和分析CBUs排斥反应的常见因素,标记排斥标准的主要原因。在这项研究中,结果显示婴儿的出生体重或母亲的年龄对排异反应没有任何影响。其他因素的结果将被讨论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Criteria for Accepting or Rejecting Cord Blood Units
Rare hematopoietic stem cell populations are responsible for the transplantation engraftment process. Umbilical cord blood (UCB) is usually processed to the total nucleated cell (TNC), but not to the mononuclear cell (MNC) fraction. TNC counts are used to determine UCB unit storage, release for transplantation and correlation with time to engraftment [1]. It has been mentioned in the literature that there are several factors that affect harvesting of cord blood stem cells [2]. It was set to analyze the relationship between fetal weight and other factors that led to rejection of CBUs brought to DCRC from public and private donations. In this retrospective study, 375 donations of CBUs from January 2018 to October 2018 at DCRC were recorded. From literature, factors that are usually involved in rejection of CBUs were recorded and analyzed to mark the leading cause of rejection criteria. In this study, it showed that results did not find infants’ birth weight or mother’s age to have any value in rejection. Other factors’ results will be discussed.
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来源期刊
CiteScore
0.60
自引率
10.00%
发文量
69
审稿时长
12 weeks
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