青少年物质使用障碍的评估和治疗资源

Q3 Pharmacology, Toxicology and Pharmaceutics
E. Pender, Liana Kostak, Kelsey Sutton, Cody Naccarato, A. Tsai, T. Chung, Stacey B. Daughters
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引用次数: 0

摘要

物质使用障碍(SUD)被理解为持续使用物质,损害个人的生计和健康。如果处理不当,SUD会对精神、身体和社会产生严重影响。虽然SUD可以在任何年龄发生,但考虑到某些物质(如大麻)在该年龄组的患病率上升以及与早发性SUD相关的预后不良,解决青少年的SUD尤为重要[1][2]。来自全国药物使用和健康调查的数据显示,12-17岁人群终生使用非法药物的比例为20.9%[3]。同一项调查发现,在过去一年中,使用非法药物或酒精的12-17岁人群中物质使用障碍的比例在2020年为6.3%[3]。本文旨在帮助临床医生和外行人更深入地了解青少年的SUD,特别是与酒精、大麻、尼古丁和阿片类药物有关的SUD。虽然酒精、大麻和尼古丁是全国这一年龄段人口最常用的物质[4],但阿片类药物的使用——以及由此导致的死亡——一直在上升。根据美国疾病控制与预防中心(CDC)的数据,在2020年近92,000例药物死亡中,约75%与阿片类药物有关[5]。除了普通人群的高死亡率外,最近与合成阿片类药物芬太尼相关的青少年死亡率飙升——从2010年到2019年,芬太尼的死亡率保持相对稳定,直到2019年至2020年增长94%,到2021年又增长20%——值得对这一人群的阿片类药物进行调查[6]。如果管理不当,这些物质中的每一种都可能对健康产生不利的长期影响,导致严重损害终身福祉[7]。本文探讨了与青少年相关的SUD患病率和诊断标准,包括DSM-IV和DSM-5之间SUD分类变化的概述,以及ICD-11和研究领域标准(RDoC)作为物质使用相关研究的基础的讨论。有效的评估和考虑共同发生的疾病也包括在内。虽然SUD的预后因个体的环境和情况而异,但本文讨论了SUD的模式发展过程。最后,提供了一份国家认可的资源清单,包括热线、治疗定位器、信息网站和支持小组,以及汇编当地资源的工具。通过研究青少年SUD的这些方面,研究小组提供了一个更广泛的视角,了解其在美国的患病率,主要的警告信号和合并症,以及对青少年SUD的可能评估和治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Resources for the Assessment and Treatment of Substance Use Disorder in Adolescents
Substance Use Disorder (SUD) is understood as the persistent use of substances to the detriment of the individual's livelihood and wellness. SUD can have serious mental, physical, and social ramifications if not properly addressed. Though SUD can develop at any age, it is especially important to address in adolescents, given the rising prevalence of certain substances (e.g. cannabis) in that age group and the poor prognosis associated with early-onset SUD[1][2]. Data from the National Survey on Drug Use and Health show the lifetime use of illicit drugs in people ages 12-17 is 20.9%[3] The same survey found the rate of Substance Use Disorder in the past year for people ages 12-17 who used illicit drugs or alcohol to be 6.3% in 2020[3]. This paper is intended for clinicians and laypeople to gain a deeper understanding of SUD in adolescents, particularly relating to alcohol, cannabis, nicotine, and opioids. Though alcohol, cannabis, and nicotine are the substances most commonly used by this age demographic nationally[4], opioid use – and resulting deaths – have been on the rise. According to the Centers for Disease Control and Prevention (CDC), opioids were connected to about 75% of the nearly 92,000 drug deaths in 2020[5]. Beyond significant death rates in the general population, recent spikes in adolescent death rates tied to the synthetic opioid fentanyl – which held a relatively stable death rate from 2010 to 2019 until seeing a 94% increase from 2019 to 2020 and an additional 20% increase to 2021 - warrants inquiry into opioids for this population[6]. Each of these substances can have adverse, long-lasting effects on health if not managed properly, resulting in seriously compromised lifelong well-being [7]. This article explores SUD prevalence and reviews diagnostic criteria in relation to adolescence, including a synopsis of changes in SUD classification between the DSM-IV and DSM-5 and a discussion of ICD-11 and the Research Domain Criteria (RDoC) as a basis for research related to substance use. Effective assessment and consideration of co-occurring disorders are covered as well. Although the prognosis of SUD varies by an individual's environment and circumstances, a modal developmental course for SUD is discussed. Finally, a curated list of nationally recognized resources including hotlines, treatment locators, informational sites, and support groups are provided, along with tools to compile local resources. By addressing these aspects of adolescent SUD, the research team offers a broader view of its prevalence in the United States, key warning signs and comorbidities, and possible assessments and treatments for adolescents with SUD.
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来源期刊
WikiJournal of Medicine
WikiJournal of Medicine Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
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6
审稿时长
4 weeks
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