子宫内膜异位症的基因测定

Mihaela Țurcan, O. Maioru, L. Pop, V. Rădoi, R. Ursu, N. Bacalbaşa, I. Bălescu, Ioan Dumitru Suciu
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引用次数: 0

摘要

子宫内膜异位症是一种影响育龄妇女的衰弱性疾病,与慢性盆腔疼痛、痛经、性交困难和不孕症等严重症状有关。目前该病的发病机制尚不完全清楚,提出了多种理论。然而,最近,人们的注意力集中在确定遗传因素在子宫内膜异位症发展中的作用。在本文中,我们旨在回顾有关发病机制的最重要的理论。此外,我们还讨论了有关这种疾病的遗传因素以及其他被怀疑是导致这种病理的罪魁祸首的基因。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Genetic determination in endometriosis
Endometriosis represents a debilitating disease affecting women at fertile age which is associated with severe symptoms such as chronic pelvic pain, dysmenorrhea, dyspareunia and infertility. The pathogenesis of this disease is not fully understood so far, multiple theories being proposed. However, more recently, attention was focused on identifying the role of genetic factors in endometriosis development. In the current paper we aimed to review the most important theories regarding pathogenesis. Furthermore we discuss the genetic factors regarding this illness as well as other genes that are suspected to be culprits in leading to this pathology.
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