根治性手术治疗非肿瘤性结肠疾病

IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL
V. Melnyk
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引用次数: 0

摘要

的目标。通过优化根治性手术范围的选择,提高非肿瘤性结肠疾病患者的手术治疗效果。材料和方法。研究资料是对87例非肿瘤性结肠疾病患者进行根治性手术干预的分析:溃疡性结肠炎、克罗恩病、家族性腺瘤性息肉病、慢性结肠和结肠原性停滞、结肠憩室病。手术患者年龄20 ~ 72岁。男性49例(56.3%),女性38例(43.7%)。确定并证实了这些疾病的根治性手术范围的选择标准。在溃疡性结肠炎和克罗恩病急性并发症的绝对指征手术患者中,有3例术后死亡率(3.4%)。溃疡性结肠炎、克罗恩病和家族性腺瘤性息肉病在16例(18.4%)手术患者中复发于直肠残端和回肠末端。5例(5.7%)复发患者发生直肠残端恶性转化。非肿瘤性结肠疾病根治性手术的程度取决于基础疾病的诊断、并发症的存在、肠壁病变的深度、病理过程的程度、小肠和大肠解剖部位的复发风险。手术干预的根治性分期取决于诊断、非肿瘤性结直肠疾病的临床病程特点、复发率、患者的一般情况、病理过程的程度和严重程度。对非肿瘤性结肠疾病进行最佳程度的根治性手术有助于将小肠末端的复发率降低到4例(4.6%),将直肠残端区域的复发率降低到7例(8.1%),改善了76例(87.3%)手术患者的功能结局和生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Radical surgery for non-neoplastic colonic diseases
Aim. To improve the results of surgical treatment for patients with non-neoplastic colonic diseases by optimizing the choice of radical surgery extent. Materials and methods. The study material was the analysis of radical surgical interventions performed in 87 patients with non-neoplastic colonic diseases: ulcerative colitis, Crohn’s disease, familial adenomatous polyposis, chronic colonic and coloproctogenic stasis, diverticular colon disease. The age of the operated patients was 20–72 years. There were 49 (56.3 %) men and 38 (43.7 %) women. The criteria for choosing the radical surgery extent for these diseases were defined and substantiated. Results. There were 3 postoperative mortalities (3.4 %) among patients operated on absolute indications for acute complications of ulcerative colitis and Crohn’s disease. Recurrences of ulcerative colitis, Crohn’s disease and familial adenomatous polyposis occurred in 16 (18.4 %) operated patients in the area of the retained rectal stump and terminal ileum. Malignant transformation of the rectal stump occurred in 5 (5.7 %) patients with these recurrences. The extent of radical surgery in non-neoplastic colonic diseases depended on the diagnosis of the underlying disease, the presence of complications, the depth of wall lesions and the extent of the pathological process, the risk of recurrence in the anatomical parts of the small and large intestine. Conclusions. Deciding on the extent of the radical stage of surgical intervention depended on the diagnosis, features of the clinical course of non-neoplastic colorectal diseases, recurrences, the general condition of a patient, the pathological process extent and severity. Performing the optimal extent of radical surgery for non-neoplastic colonic diseases helped reduce the number of recurrences in the terminal part of the small intestine to 4 (4.6 %), in the area of the rectal stump to 7 (8.1 %), improved functional outcomes and quality of life in 76 (87.3 %) operated patients.
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来源期刊
Zaporozhye Medical Journal
Zaporozhye Medical Journal MEDICINE, GENERAL & INTERNAL-
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发文量
72
审稿时长
8 weeks
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