气体造影剂在常规和谐波多普勒测量中的光谱展宽

W. Shi, F. Forsberg, H. Oung
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引用次数: 14

摘要

气体造影剂可以用来增强传统的多普勒测量和创建新的谐波多普勒模式。利用体外脉冲流系统研究了气泡破坏对常规和谐波多普勒频谱的影响。在相同流量的常规多普勒测量和谐波多普勒测量中,在低水平的失谐(低于0.62 MPa)下观察到类似的频谱图。随着声输出增大(达到1.8 MPa),谱图显示出明显的谱宽,尤其是谐波多普勒谱。光谱展宽是由气泡破坏引起的透射时间效应引起的。这一发现被一个类似的实验证实,实验对象是悬浮在凝胶幻影中的固定聚合物包覆微泡。总之,在用气体造影剂进行常规和谐波多普勒测量时都应考虑气泡破坏的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Spectral broadening in conventional and harmonic Doppler measurements with gaseous contrast agents
Gaseous contrast agents can be used to enhance conventional Doppler measurements and to create new harmonic Doppler modalities. The effect of bubble destruction on both conventional and harmonic Doppler spectra was studied using an in vitro, pulsatile flow system. Similar spectrograms were observed for low levels of insonification (below 0.62 MPa) in both conventional and harmonic Doppler measurements of the same flow. As the acoustic output was increased (up to 1.8 MPa) the spectrograms showed marked spectral broadening, especially for harmonic Doppler. The spectral broadening was caused by transit time effects resulting from the destruction of insonated bubbles. This finding was confirmed by performing a similar experiment on stationary polymer-coated microbubbles suspended in a gel phantom. In conclusion, the effect of bubble destruction should be taken into account in both conventional and harmonic Doppler measurements with gaseous contrast agents.
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