{"title":"海盐基口腔冲洗液对高龋易感性牙龈炎患者变形链球菌水平和口腔生态影响的随机临床研究","authors":"Amit Mani, S. Mani, R. Saini","doi":"10.7439/IJBAR.V9I4.4730","DOIUrl":null,"url":null,"abstract":"Background: The etiologic role of a pathogenic dental plaque biofilm in the development of gingivitis and dental caries is well documented. This study evaluates the rationale for incorporating sea salt based mouth rinse into a daily oral hygiene regimen along with mechanical plaque control methods on gingival inflammation and caries susceptibility level in mild to moderate gingivitis patients. Methods: A prospective, double-blinded, randomized parallel-group controlled study involving 40subjects was conducted to assess efficacy and safety. Subjects were randomized to receive either the study rinse (H2Ocean)or a water-only preparation. The oral hygiene index (OHI) and S. Mutans Level were measured at baseline and at the end of the study period. Results: Sea salt mouth rinse was significantly better than the control, with respect to both the change in OHI score by 28.89% and S. mutans level by 35%. No adverse effects were noted in any of the study groups. Conclusion: Sea Salt mouth rinse is a safe and effective treatment for preventing the development of gingival inflammation and S. mutans level in mild to moderate gingivitis population. Further research is needed to evaluate its long-term effects.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"22 1","pages":"167-170"},"PeriodicalIF":0.0000,"publicationDate":"2018-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Effects of Sea Salt Based Oral Rinse on Streptococcus Mutans Level and Oral Ecology in Gingivitis Subjects with High Caries Susceptibility: A Randomized Clinical Study\",\"authors\":\"Amit Mani, S. Mani, R. Saini\",\"doi\":\"10.7439/IJBAR.V9I4.4730\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: The etiologic role of a pathogenic dental plaque biofilm in the development of gingivitis and dental caries is well documented. This study evaluates the rationale for incorporating sea salt based mouth rinse into a daily oral hygiene regimen along with mechanical plaque control methods on gingival inflammation and caries susceptibility level in mild to moderate gingivitis patients. Methods: A prospective, double-blinded, randomized parallel-group controlled study involving 40subjects was conducted to assess efficacy and safety. Subjects were randomized to receive either the study rinse (H2Ocean)or a water-only preparation. The oral hygiene index (OHI) and S. Mutans Level were measured at baseline and at the end of the study period. Results: Sea salt mouth rinse was significantly better than the control, with respect to both the change in OHI score by 28.89% and S. mutans level by 35%. No adverse effects were noted in any of the study groups. Conclusion: Sea Salt mouth rinse is a safe and effective treatment for preventing the development of gingival inflammation and S. mutans level in mild to moderate gingivitis population. Further research is needed to evaluate its long-term effects.\",\"PeriodicalId\":13848,\"journal\":{\"name\":\"International Journal of Biomedical and Advance Research\",\"volume\":\"22 1\",\"pages\":\"167-170\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Biomedical and Advance Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.7439/IJBAR.V9I4.4730\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Biomedical and Advance Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7439/IJBAR.V9I4.4730","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effects of Sea Salt Based Oral Rinse on Streptococcus Mutans Level and Oral Ecology in Gingivitis Subjects with High Caries Susceptibility: A Randomized Clinical Study
Background: The etiologic role of a pathogenic dental plaque biofilm in the development of gingivitis and dental caries is well documented. This study evaluates the rationale for incorporating sea salt based mouth rinse into a daily oral hygiene regimen along with mechanical plaque control methods on gingival inflammation and caries susceptibility level in mild to moderate gingivitis patients. Methods: A prospective, double-blinded, randomized parallel-group controlled study involving 40subjects was conducted to assess efficacy and safety. Subjects were randomized to receive either the study rinse (H2Ocean)or a water-only preparation. The oral hygiene index (OHI) and S. Mutans Level were measured at baseline and at the end of the study period. Results: Sea salt mouth rinse was significantly better than the control, with respect to both the change in OHI score by 28.89% and S. mutans level by 35%. No adverse effects were noted in any of the study groups. Conclusion: Sea Salt mouth rinse is a safe and effective treatment for preventing the development of gingival inflammation and S. mutans level in mild to moderate gingivitis population. Further research is needed to evaluate its long-term effects.