海盐基口腔冲洗液对高龋易感性牙龈炎患者变形链球菌水平和口腔生态影响的随机临床研究

Amit Mani, S. Mani, R. Saini
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引用次数: 1

摘要

背景:一种病原性牙菌斑生物膜在牙龈炎和龋齿发生中的病原学作用已被充分证实。本研究评估将海盐漱口水纳入日常口腔卫生方案的基本原理以及机械菌斑控制方法对轻度至中度牙龈炎患者牙龈炎症和龋齿易感性水平的影响。方法:采用前瞻性、双盲、随机、平行组对照研究,评估40例受试者的疗效和安全性。受试者随机接受研究漂洗剂(H2Ocean)或纯水制剂。在研究开始时和研究结束时测量口腔卫生指数(OHI)和变形链球菌水平。结果:海盐漱口水对OHI评分和变形链球菌水平的影响分别为28.89%和35%,明显优于对照组。在任何研究组中均未发现不良反应。结论:海盐漱口水是一种安全有效的治疗方法,可预防轻中度牙龈炎人群牙龈炎症的发展和变形链球菌的水平。需要进一步的研究来评估其长期影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of Sea Salt Based Oral Rinse on Streptococcus Mutans Level and Oral Ecology in Gingivitis Subjects with High Caries Susceptibility: A Randomized Clinical Study
Background: The etiologic role of a pathogenic dental plaque biofilm in the development of gingivitis and dental caries is well documented. This study evaluates the rationale for incorporating sea salt based mouth rinse into a daily oral hygiene regimen along with mechanical plaque control methods on gingival inflammation and caries susceptibility level in mild to moderate gingivitis patients. Methods: A prospective, double-blinded, randomized parallel-group controlled study involving 40subjects was conducted to assess efficacy and safety. Subjects were randomized to receive either the study rinse (H2Ocean)or a water-only preparation. The oral hygiene index (OHI) and S. Mutans Level were measured at baseline and at the end of the study period. Results: Sea salt mouth rinse was significantly better than the control, with respect to both the change in OHI score by 28.89% and S. mutans level by 35%.  No adverse effects were noted in any of the study groups. Conclusion: Sea Salt mouth rinse is a safe and effective treatment for preventing the development of gingival inflammation and S. mutans level in mild to moderate gingivitis population. Further research is needed to evaluate its long-term effects.
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