使用Mini-Cog筛查中国老年人可能患痴呆症的担忧

Kar Choi Chan , Joel Sadavoy
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引用次数: 2

摘要

Mini-Cog是一种易于管理和可靠的可能的痴呆短屏幕。据说它具有与迷你精神状态检查(MMSE)相当的高灵敏度和特异性。它由延迟回忆(DR)测试和干扰器时钟绘制测试(CDT)组成。阳性筛查定义为3项DR得分为0或DR得分为1-2并伴有异常CDT。据说,Mini-Cog相对来说没有语言、教育和文化偏见。然而,Mini-Cog在筛选受过很少教育或没有受过教育的少数民族老年人方面的效用在很大程度上仍未得到探索。方法从多伦多7个社会娱乐项目中招募96名居住在社区的华人老年人,通过Mini-Cog对可能的痴呆进行筛查。评估了使用Mini-Cog进行筛选的可行性和局限性。通过评估问卷收集参与者对Mini-Cog可接受性的反馈和对未来Mini-Cog筛查的抵制。使用Fisher精确检验来确定参与者拒绝尝试或完成Mini-Cog与每个相关变量之间是否存在显著关联,即1)参与者的读写能力;2)对Mini-Cog重筛的阻力;3)难以理解Mini-Cog指令;4) Mini-Cog的DR部分的性能。结果96例患者中有10例(10.4%)拒绝尝试Mini-Cog的CDT部分,并表现出书写和绘图困难。在这10人中,7人没有接受过教育,3人接受过最低程度的教育。参与者拒绝尝试CDT与文盲之间存在高度显著的关联(p=7E−0;术中,0.001)。虽然参与者拒绝尝试Mini-Cog的CDT部分似乎与他们自我报告的理解Mini-Cog指导的困难或他们在筛选中的实际DR分数无关,但发现它与他们对未来Mini-Cog测试的抵抗力显著相关(p=0.4958;术中,0.05)。结论Mini-Cog在低文化程度老年人筛查中的应用可能存在局限性。这与早期关于文盲对CDT表现的负面影响的发现相一致。需要进一步的研究来探索对Mini-Cog的干扰成分进行可能的修改,以适应文盲或教育水平很低的老年人。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Concerns of using the Mini-Cog to screen Chinese elders for possible dementia

Introduction

The Mini-Cog is an easy-to-administer and reliable short screen for possible dementia. It is said to have high sensitivity and specificity comparable to those of Mini Mental Status Examination (MMSE). It consists of a delayed-recall (DR) test and a distractor-clock-drawing test (CDT). A positive screen is defined as either a score of zero in the 3-item DR or a score of 1–2 in the DR combined with an abnormal CDT. The Mini-Cog is said to be relatively free of language, educational and cultural bias. However the utility of the Mini-Cog for screening ethnic elders with minimal or no education remains largely unexplored.

Methods

Ninety-six community-dwelling Chinese elders from 7 social-recreational programs in Toronto were recruited and screened by the Mini-Cog for possible dementia. The feasibility and limitations of using the Mini-Cog for screening were evaluated. Participants' feedback on the acceptability of the Mini-Cog and their resistance to future Mini-Cog screening were collected through evaluative questionnaires. Fisher Exact test was used to determine whether there was significant association between participants' refusal to attempt or complete the Mini-Cog and each of the pertinent variables namely 1) participants' literacy; 2) resistance to the Mini-Cog re-screening; 3) difficulty understanding the Mini-Cog instruction; and 4) performance on the DR part of the Mini-Cog.

Results

Of the 96 participants, 10 (10.4%) refused to attempt the CDT part of the Mini-Cog, and expressed difficulty in writing and drawing. Of those 10, 7 reported having no education and 3 minimal education. A highly significant association was found between participants' refusal to attempt CDT and illiteracy (p=7E−0; p<0.001). While participants' refusal to attempt the CDT part of the Mini-Cog appeared to be independent of their self-reported difficulty in understanding the Mini-Cog instruction or their actual DR score in screening, it was found to be significantly related to their resistance to future mini-Cog test (p=0.4958; p<0.05).

Conclusion

The results suggest that there may be limitations in the utility of the Mini-Cog for screening elders with minimal education. This concurs with earlier findings about the negative effect of illiteracy on CDT performance. Further study is needed to explore possible modifications to the distracter component of the Mini-Cog for elders who are illiterate or have a very low level of education.

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