基于蒙特卡罗模拟的伽玛刀图标™单扇区表征

Q3 Health Professions
A. Ameri, G. Geraily
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引用次数: 0

摘要

目的:伽玛刀放射外科是指利用辐射破坏颅内难以捉摸或不适合开腹手术的组织或病变的手术。本研究旨在模拟伽玛刀图标™(GKI™)单扇区,以评估输出光束的各种属性,并评估EGSnrc c++蒙特卡罗代码的能力,以执行GKI™的完整模拟,以进行更多的研究。材料和方法:模拟单源,根据制造商数据定义4和16 mm准直器的几何形状。在每个准直器末端记录相空间文件(psf),并保存剂量分布以供最后一步的最终分析过程使用。结果:束谱有两个能量峰g1 =1.17 MeV和g2 = 1.33 MeV,且有明显的低能量散射光子。在将模拟产生的剂量曲线与参考数据进行比较时,伽马指数(GI)值小于1。在x、y和z轴上,4mm和16mm准直器的全宽度分别为4.55、10.9、5.13 (mm)和16.7、35.1、17.65 (mm)。在x、y和z轴上,4mm和16mm准直器的半影宽度(80%-20%)分别为1.48、5.5、1.54 (mm)和3.76、10.1、2.78 (mm)。结论:结果与预期的很好地一致,并且可以使用egg++对GKI™系统进行完整的模拟,以便在幽灵和患者中进行更多的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Gamma Knife Icon™ Single Sector Characterization Based on Monte Carlo Simulation
Purpose: Gamma Knife Radiosurgery refers to surgery using radiation to destroy intracranial tissues or lesions elusive or unsuitable for open surgery. This study aimed to simulate the Gamma Knife Icon™ (GKI™) single sector to assess various attributes of the output beam and evaluate the EGSnrc C++ Monte Carlo code capabilities to perform a complete simulation of GKI™ for more investigations. Materials and Methods: The single source is simulated, and the geometries of the 4 and 16 mm collimators are defined based on the manufacturer data. The phase space files (PSFs) are recorded at the end of each collimator, and dose distributions are saved for the final analysis process in the last step. Results: The beam spectrum has two energy peaks g1 =1.17 MeV and g2 = 1.33 MeV, and low energy photons from scattering are also evident. The Gamma Index (GI) values are less than 1 in comparing the dose profiles generated in simulation with reference data. The Full Width at Half Maximum (FWHM) is 4.55, 10.9, 5.13 (mm) and 16.7, 35.1, 17.65 (mm) for 4mm and 16 mm collimators along x, y, and z axes, respectively. The penumbra width (80%-20%) is also 1.48, 5.5, 1.54 (mm) and 3.76, 10.1, 2.78 (mm) for 4mm and 16 mm collimators along x, y, and z axes, respectively. Conclusion: Results are in good agreement with what is expected, and it is possible to perform a complete simulation of the GKI™ system using egs++ for more investigations in phantoms and patients.
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来源期刊
Frontiers in Biomedical Technologies
Frontiers in Biomedical Technologies Health Professions-Medical Laboratory Technology
CiteScore
0.80
自引率
0.00%
发文量
34
审稿时长
12 weeks
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