Two new Cu(II) and Zn(II) Schiff base complexes: Synthesis, characterization and their biological activity

A B S T RA C T : New two nano- sized Schiff base complexes [M(L)], where L= 2, 2'-((1E, 1E')-(1, 2 phenylen bis (azanylylidene)) bis (methanylylidene)) bis (4-bromo phenolato) and M=Cu or Zn, (a, b complexes) were synthesized by ultrasonic irradiation. These complexes were characterized by elemental analysis, molar conductivity, FT-IR, fluorescence emission, 1 H NMR, field emission scanning electron spectroscopy (FESEM) and UV-Vis spectroscopy. The UV-Vis spectroscopic data and fluorescence emission bands of these nano-sized Schiff base complexes show a shift in comparison with the bulk sample analogue, due to the reduction in particle size to nano scale. In vitro antimicrobial activities of the title compounds against some Gram-positive (Staphylococcus aureus, Micrococcus luteus, Bacillus cereus, Eterococcus faecalis) and Gram-negative bacteria (Pseudomonas aeruginosa, Escherichia coli, Klebsiella sp, Pscudomonas sp) and fungus strain (Candida albicans) were investigated and compared with each other. It was found that Cu (II) complex showed higher antibacterial activity than the Zn (II) complex.