3D打印在制药科学中的应用,以及载药复合材料给药途径的评价

Q4 Pharmacology, Toxicology and Pharmaceutics
M. Khatami, A. Doniavi, S. Allahyari, Mahsa Feizollahi, A. Abazari, M. Fotouhi
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引用次数: 1

摘要

3D打印技术是医药领域的新技术,但其应用尚未完全确立。这种方法可以促进药物治疗,并以不同的方式克服一些传统治疗的挑战,本文将对此进行讨论。“一刀切”、大规模生产、患者和医生接受度较低是传统治疗的局限性。医药产品的三维打印,是一项需要特别注意的多用途技术。基于液滴、基于挤压和激光辅助的3D打印机是可用于该领域的三种主要技术。讨论了该方法的局限性和优点,强调了药物载体在油墨配方中使用的潜在创新途径。载药复合材料的给药途径是本文讨论的药物治疗策略中的另一个重要问题。口服给药作为一种方便的全身给药方法,具有很大的患者偏好,是3D打印药物研究中最普遍的途径。最后,概述了3D打印在制药和医疗保健行业的基本伦理和未来方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Application of 3D Printing in Pharmaceutical Sciences, and Evaluation of Administration Routes for Drug-Loaded Composites
3D printing is novel approach in pharmaceutical field, but its usage has not yet fully established. This method can promote drug therapy and overcome some traditional treatment challenges in different ways that are discussed at this paper. "One-size-fits-all", Large-scale production, and less patient and physician acceptability are some limitations that we will encounter in traditional therapy. Three-dimensional printing of pharmaceutical products, is a versatile technology that needs specific attention. droplet-based, extrusion-based, and laser-assisted 3D printers are three main techniques that can be used in this field. The limitations and advantages of this method are also discussed, highlighting potential innovative pathways towards the possibility of drug carriers’ usage in ink formulas. The administration pathway of drug-loaded composites is another important issue in drug treatment strategies that has been discussed here. Oral drug delivery as a convenient method of systemic drug administration with great patient preference, is introduced as a most prevalent pathway that has been studies about 3D printed medicines. Finally, essential ethics and future directions of 3D printing in the pharmaceutical and healthcare industries are outlined.
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来源期刊
CiteScore
0.10
自引率
0.00%
发文量
17
审稿时长
10 weeks
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