Primary Superficial Ewing Sarcoma with lymph node metastasis: unusual presentation (Case report and review of literatures)

Primary superficial Ewing sarcoma (PSES) is an extremely uncommon tumor. Although Ewing sarcoma (ES) is primarily a bone tumor, it can sporadically affect the deep subcutaneous tissue or muscles, and it rarely occurs as a primary skin cancer. In contrast to bone or deep-seated Ewing sarcoma, superficial Ewing's sarcoma appears to have a better prognosis and rarely metastasizes. We report the case of a 21-year-old female who presented with a 1-year history of progressive enlarged right anterior thigh mass. The tumor was excised as a mass measuring 9×7×5 cm with a lymph node of 2×2 cm in size and sent for histopathology. Histopathological and immunohistochemical studies confirmed the diagnosis of PSES with lymph node metastasis, and the patient is now on treatment.