{"title":"联合用药对犬弓形虫卵的卵泡活性体外实验研究","authors":"R. Safiullin","doi":"10.31016/978-5-6048555-6-0.2023.24.408-413","DOIUrl":null,"url":null,"abstract":"To control helminth infections in carnivores, scientists and practitioners have \nproposed a number of drugs and agents against both endogenous and exogenous \nstages. The problem of toxocariasis in carnivores continues to pose challenges for \nresearchers, namely, to improve measures to control the exogenous stage of egg \ndevelopment. Of the modern drugs used against the exogenous stages of Toxocara \negg development in carnivores, we should note chlorine-, phenol-, iodine-, caustic \nalkalis-based drugs and others which are mostly monovalent and do not meet the \nrequirements of veterinary practice in terms of their efficacy. Based on the above, \nwe set ourselves the task of testing the ovocidal activity of the combined agent \nСystodesis consisting of glutaraldehyde, alkyldimethylbenzylammonium chloride, \nisopropyl alcohol, and polyethylene glycol-400 against Toxocara canis eggs in an \nin vitro laboratory experiment. The combined agent of disinvasion Сystodesis at \n3% concentration showed 94.06% intense-effectiveness in an in vitro laboratory \nexperiment against Toxocara canis eggs. The intense-effectiveness of the test agent at \n4 and 5% concentrations against Toxocara eggs in dogs was 100%. The comparator \n4% phenol provided 86.5% intense-effectiveness.","PeriodicalId":22969,"journal":{"name":"THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL","volume":"40 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"OVOCIDAL ACTIVITY OF THE COMBINED DRUG AGAINST TOXOCARA CANIS EGGS IN AN IN VITRO LABORATORY EXPERIMENT\",\"authors\":\"R. Safiullin\",\"doi\":\"10.31016/978-5-6048555-6-0.2023.24.408-413\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"To control helminth infections in carnivores, scientists and practitioners have \\nproposed a number of drugs and agents against both endogenous and exogenous \\nstages. The problem of toxocariasis in carnivores continues to pose challenges for \\nresearchers, namely, to improve measures to control the exogenous stage of egg \\ndevelopment. Of the modern drugs used against the exogenous stages of Toxocara \\negg development in carnivores, we should note chlorine-, phenol-, iodine-, caustic \\nalkalis-based drugs and others which are mostly monovalent and do not meet the \\nrequirements of veterinary practice in terms of their efficacy. Based on the above, \\nwe set ourselves the task of testing the ovocidal activity of the combined agent \\nСystodesis consisting of glutaraldehyde, alkyldimethylbenzylammonium chloride, \\nisopropyl alcohol, and polyethylene glycol-400 against Toxocara canis eggs in an \\nin vitro laboratory experiment. The combined agent of disinvasion Сystodesis at \\n3% concentration showed 94.06% intense-effectiveness in an in vitro laboratory \\nexperiment against Toxocara canis eggs. The intense-effectiveness of the test agent at \\n4 and 5% concentrations against Toxocara eggs in dogs was 100%. The comparator \\n4% phenol provided 86.5% intense-effectiveness.\",\"PeriodicalId\":22969,\"journal\":{\"name\":\"THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL\",\"volume\":\"40 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-04-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31016/978-5-6048555-6-0.2023.24.408-413\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31016/978-5-6048555-6-0.2023.24.408-413","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
OVOCIDAL ACTIVITY OF THE COMBINED DRUG AGAINST TOXOCARA CANIS EGGS IN AN IN VITRO LABORATORY EXPERIMENT
To control helminth infections in carnivores, scientists and practitioners have
proposed a number of drugs and agents against both endogenous and exogenous
stages. The problem of toxocariasis in carnivores continues to pose challenges for
researchers, namely, to improve measures to control the exogenous stage of egg
development. Of the modern drugs used against the exogenous stages of Toxocara
egg development in carnivores, we should note chlorine-, phenol-, iodine-, caustic
alkalis-based drugs and others which are mostly monovalent and do not meet the
requirements of veterinary practice in terms of their efficacy. Based on the above,
we set ourselves the task of testing the ovocidal activity of the combined agent
Сystodesis consisting of glutaraldehyde, alkyldimethylbenzylammonium chloride,
isopropyl alcohol, and polyethylene glycol-400 against Toxocara canis eggs in an
in vitro laboratory experiment. The combined agent of disinvasion Сystodesis at
3% concentration showed 94.06% intense-effectiveness in an in vitro laboratory
experiment against Toxocara canis eggs. The intense-effectiveness of the test agent at
4 and 5% concentrations against Toxocara eggs in dogs was 100%. The comparator
4% phenol provided 86.5% intense-effectiveness.