腰椎间盘突出症患者维生素D3水平低的患病率及其与不同患者参数的关系

R. Qazi, Lal Rehman, Farrukh Javeed, Sana Akbar Qazi, T. Ahmed, Asad Abbas
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摘要

目的:了解腰椎间盘突出症患者维生素D3水平低的患病率及其与不同患者参数的关系。材料与方法:本研究是一项前瞻性研究,于2018年2月至2019年4月在真纳研究生医学中心神经外科开展的100例患者。评估腰椎间盘突出患者的血清维生素D水平和其他特征。低水平的维生素D被定义为不足(10 ng/ml - 30 ng/ml)和缺乏(< 10 ng/ml)。结果:在研究的100名患者中,只有21%的患者血清维生素D3水平最佳,79%的患者维生素缺乏症(57%不足,22%缺乏)。维生素D水平低在所有年龄组中都很普遍,在老年组中缺乏更为普遍(p值= 0.004)。患者的身体质量指数(BMI)与维生素D水平呈线性相关。结论:腰椎间盘突出症患者普遍存在维生素D水平下降。研究表明,老年患者和高BMI表现出严重的维生素D缺乏症。因此,建议针对这一特定维生素缺乏症的预防措施针对更广泛的人群,以阻止维生素D水平低的发生及其相关影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Prevalence of Low Vitamin D3 Levels in Patients with Lumbar Disc Herniation and Its Relationship with Different Patient Parameters
Objective:  To determine the prevalence of low vitamin D3 levels in patients having proven lumbar disc herniation and its relationship with different patient parameters. Materials and Methods:  This is a prospective study carried out on 100 patients at the Neurosurgery department, Jinnah postgraduate medical center from Feb 2018 to April 2019. Serum Vitamin D levels and other characteristics were assessed in patients with prolapsed lumbar intervertebral discs. Low levels of Vitamin D were defined as insufficiency (10 ng/ml – 30 ng/ml) and deficiency (< 10 ng/ml). Results:  Out of 100 patients in the study, only 21% had optimal serum vitamin D3 levels, and 79% had hypovitaminosis (57% insufficient and 22% deficiency). Low vitamin D levels were prevalent in all age groups, with deficiency more prevalent in the older age group (p-value = 0.004). The BMI (body mass index) of the patients showed a linear correlation with vitamin D levels. Conclusion:  Decreased vitamin D levels are prevalent in patients having herniated lumbar discs. The study showed that older-aged patients and high BMI exhibited severe vitamin D deficiency. As a result, recommendations are that preventive initiative for this specific hypovitaminosis target a broader population to intercept the occurrence of low vitamin D levels and the associated repercussions.
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