糖尿病皮肤表现谱:一项来自三级医院的观察性研究

A. Baidya, A. Halder, P. Datta
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摘要

导读:糖尿病会导致全身的破坏,皮肤也不能幸免。皮肤是一个活跃的代谢组织,具有急性总体代谢紊乱和糖尿病慢性退行性变化的双重影响。目的和目的:研究印度东部地区糖尿病皮肤病学表现的临床模式。方法:连续60例有皮肤病表现并符合纳入标准的糖尿病患者纳入研究。结果:细菌感染是最常见的皮肤病(46.7%)。不同形式的皮肤真菌感染和念珠菌感染分别占30%和23.3%。糖尿病性皮肤病或“胫斑”和糖尿病足伴坏疽变化分别占20%和13.3%。与糖尿病相关的皮肤表现是第二常见的皮肤疾病,占43.3%(60例中有26例)。来历不明的瘙痒和干燥症(13.3%)是糖尿病患者中最常见的皮肤异常。其他皮肤表现,如色素性紫癜性皮肤病(6.6%)、银屑病(3.3%)、白癜风(6.6%)、扁平苔藓(3.3%)、多孔性骨质疏松症(3.3%)、硬化症、糖尿病性皮肤增厚及挛缩(6.6%)、脂肪营养不良(3.3%)、皮疹(6.6%)和疤痕伴脓肿(1.6%),均非常罕见。结论:我们的研究对糖尿病的皮肤病学表现模式提供了一些见解。一项更大的前瞻性研究将进一步巩固我们的主要目标,即糖尿病的管理是一个整体,对皮肤并发症的适当关注是必要的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Spectrum of Cutaneous Manifestations of Diabetes Mellitus: An Observational Study from a Tertiary Care Hospital
Introduction: Diabetes leads to destruction all over the body and the skin is not exempted from the attack. The skin shares both the effects of acute gross metabolic derangement and chronic degenerative changes of diabetes, as it are an actively metabolizing tissue.Aims and objectives: To study the clinical patterns of dermatological manifestations of diabetes mellitus in the region of eastern India.Methods: Sixty consecutive subjects with diabetes mellitus having dermatological manifestations and satisfying the inclusion criteria were included in this study.Results: Bacterial infections were the commonest dermatological disorder (46.7%). Different forms of dermatophyte infections and candidiasis were found in 30% and 23.3% subjects, respectively. Diabetic dermopathy or ‘shin spot’ and diabetic foot with gangrenous changes were found in 20% and 13.3% subjects, respectively. Skin manifestations associated with diabetes were the second most common skin disorders and constituted 43.3% (26 out of 60 cases). Pruritus of unknown origin and xerosis (13.3%) were the most common cutaneous abnormalities in the group associated with diabetes. Other cutaneous manifestations, namely pigmented purpuric dermatosis (6.6%), psoriasis (3.3%), vitiligo (6.6%), lichen planus (3.3%), porokeartosis (3.3%), sclerosis, diabetic thick skin and contracture (6.6%), lipodystrophy (3.3%), skin rashes (6.6%) and scar with abscess (1.6%), were very rare.Conclusions: Our study has provided some insights into the pattern of dermatological manifestations in diabetes mellitus. A larger prospective study will further consolidate our main objective that management of diabetes is a holistic one and due attention on skin complications is warranted.
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