博氏酵母菌对白色念珠菌生物膜的抑菌活性评价

Q4 Medicine

Infection Epidemiology and Microbiology Pub Date : 2022-09-01 DOI:10.52547/iem.8.3.243

Z. Sadeghi Ardestani, M. Yadegari, R. Kachuei

{"title":"博氏酵母菌对白色念珠菌生物膜的抑菌活性评价","authors":"Z. Sadeghi Ardestani, M. Yadegari, R. Kachuei","doi":"10.52547/iem.8.3.243","DOIUrl":null,"url":null,"abstract":") and MTT reduction reaction. The collected data were analyzed using student’s t-test in SPSS statistical software. Findings: In this study, the probiotic yeast S. boulardii reduced the pathogenicity and virulence of C. albicans in vitro. According to the results of CVS and MTT assays, a considerable reduction ( p < .001) in the biomass and viability of C. albicans biofilms was observed after 48 hours of incubation in the presence of S. boulardii extract. Conclusion: There was a significant association between S. boulardii extract concentration and biofilm formation in both CVS and MTT assays. Biofilm formation decreased with increasing S. boulardii extract concentration and incubation time in both methods compared to the control group .","PeriodicalId":34545,"journal":{"name":"Infection Epidemiology and Microbiology","volume":"113 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Assessment of Antifungal Activity of Saccharomyces boulardii against Candida albicans Biofilm\",\"authors\":\"Z. Sadeghi Ardestani, M. Yadegari, R. Kachuei\",\"doi\":\"10.52547/iem.8.3.243\",\"DOIUrl\":null,\"url\":null,\"abstract\":\") and MTT reduction reaction. The collected data were analyzed using student’s t-test in SPSS statistical software. Findings: In this study, the probiotic yeast S. boulardii reduced the pathogenicity and virulence of C. albicans in vitro. According to the results of CVS and MTT assays, a considerable reduction ( p < .001) in the biomass and viability of C. albicans biofilms was observed after 48 hours of incubation in the presence of S. boulardii extract. Conclusion: There was a significant association between S. boulardii extract concentration and biofilm formation in both CVS and MTT assays. Biofilm formation decreased with increasing S. boulardii extract concentration and incubation time in both methods compared to the control group .\",\"PeriodicalId\":34545,\"journal\":{\"name\":\"Infection Epidemiology and Microbiology\",\"volume\":\"113 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Infection Epidemiology and Microbiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52547/iem.8.3.243\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infection Epidemiology and Microbiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52547/iem.8.3.243","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

摘要

)和MTT还原反应。收集的数据在SPSS统计软件中使用学生t检验进行分析。结果:在本研究中，益生菌酵母博氏梭菌在体外降低了白色念珠菌的致病性和毒力。根据CVS和MTT试验的结果，在博氏弧菌提取物存在下孵育48小时后，观察到白色念珠菌生物膜的生物量和活力显著降低(p < 0.001)。结论:在CVS和MTT试验中，博氏弧菌提取物浓度与生物膜形成有显著相关性。与对照组相比，两种方法的生物膜形成均随博氏弧菌提取物浓度和孵育时间的增加而减少。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Assessment of Antifungal Activity of Saccharomyces boulardii against Candida albicans Biofilm

) and MTT reduction reaction. The collected data were analyzed using student’s t-test in SPSS statistical software. Findings: In this study, the probiotic yeast S. boulardii reduced the pathogenicity and virulence of C. albicans in vitro. According to the results of CVS and MTT assays, a considerable reduction ( p < .001) in the biomass and viability of C. albicans biofilms was observed after 48 hours of incubation in the presence of S. boulardii extract. Conclusion: There was a significant association between S. boulardii extract concentration and biofilm formation in both CVS and MTT assays. Biofilm formation decreased with increasing S. boulardii extract concentration and incubation time in both methods compared to the control group .

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Infection Epidemiology and Microbiology Medicine-Epidemiology

CiteScore

0.50

自引率

0.00%

发文量

审稿时长

6 weeks