病例报告:猫外耳炎增生性和坏死性

Hung-Hsien Hsiao, Pin-Chen Liu
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引用次数: 0

摘要

一只八个月大的雌性短毛家猫因双耳慢性中耳炎而被送往国立中兴大学兽医教学医院。患耳可见脓性分泌物,糜烂伴出血,双耳道口呈棕黑色增生性组织。分泌物细胞学检查显示有革兰氏阳性球菌。我们对双耳的易碎组织和增生性组织进行了组织病理学检查。根据临床和组织病理学特征,诊断为增殖性坏死性外耳炎(PNOE)。治疗开始时,使用每日两次的0.1%他克莫司软膏和每日一次的含有氢化可的松,硝酸咪康唑和硫酸庆大霉素的洗液,随后使用每日一次的抗菌冲洗,其中含有氨苄胺,醋酸乙酯脱水二钠(EDTA),用盐酸氨苄胺和去离子水缓冲至pH 8。11周后双耳无脓性排出,停用抗生素耳洗液。大多数增发性病变在17周后消退,在一年的随访期间,我们将0.1%他克莫司的剂量从每日一次减少到每周一次。然而,在我们的病例中,使用0.1%他克莫司软膏和商业耳洗剂的组合,观察到PNOE部分缓解。这只猫很健康,生活质量也很好。据我们所知,这是台湾首次报告猫患PNOE。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
CASE REPORT: PROLIFERATIVE AND NECROTIZING OTITIS EXTERNA IN A CAT
An 8-month-old intact female shorthair domestic cat was referred to the National Chung Hsing University Veterinary Medical Teaching Hospital for uncontrolled chronic otitis in both ears. The affected ears revealed purulent discharge, erosion with bleeding and brownish-black proliferative tissue in the opening of both ear canals. Cytological examination of the discharge revealed the presence of gram-positive coccoid bacteria. We carried out histopathological examinations of biopsies obtained from friable and proliferative tissues of both ears. Based on the clinical and histopathological characteristics, proliferative and necrotizing otitis externa (PNOE) was diagnosed. Treatment was initiated with a combination of twice-daily application of 0.1% tacrolimus ointment and a once-daily otic lotion containing hydrocortisone aceponate, miconazole nitrate and gentamicin sulfate following the administration of once-daily anti-bacterial flush which contains tromethamine, edetate disodium dehydrate (EDTA) buffered to pH 8 with tromethamine hydrochloride and deionized water. The antibiotic ear lotion was withdrawn in the absence of purulent discharge in both ears after 11 weeks. Most proliferative lesions resolved after 17 weeks, and we tapered the dosage of 0.1% tacrolimus from once daily to once weekly during the year follow-up period. However, in our case, partial remission of PNOE was observed with the application of a combination of 0.1% tacrolimus ointment and a commercial ear lotion. The cat was healthy and had a good quality of life. To our knowledge, this is the first report of PNOE in a cat in Taiwan.
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