以氧化锌为基础的纳米药物纳迦帕姆的表征-潜在的癌症营养补充剂

R. R., R. R
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引用次数: 1

摘要

纳迦帕帕姆是一种基于氧化锌的纳米药物,用于悉达系统。理化分析是为了使该药标准化,并了解该药的工作原理。它有抗癌活性,在自身免疫性疾病中也有,在金属和癌症中存在明显的不平衡,锌在细胞水平上被耗尽而在血浆中积累。因此,作为锌的替代品,它必须渗透到细胞中,而且它应该是无毒的,为此,那迦帕帕姆被认为是。进行了FTIR、SEM、EDAX、XRD、PL等研究。形貌分析表明,纳迦帕帕姆中存在不同大小的颗粒,颗粒大小落在纳米级。这表明该药物可以在不同的穿透深度穿透。EDAX研究证实了锌、氧、硅、镁和钾的存在。FTIR证实了ZnO、SiO2和Mg的存在。XRD证实ZnO存在于六方纤锌矿结构中。出现二次相,这主要是由于样品中存在Mg。在525 nm处的宽峰是ZnO的特征峰,从PL研究中也可以看出由于Mg的存在导致了结构的破坏,这一点在XRD中也得到了证实。综上所述,那迦帕姆是锌缺乏症自身免疫疾病和癌症的潜在替代人选。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
CHARACTERIZATION OF ZINC OXIDE BASED NANO SIDDHA MEDICINE NAGA PARPAM – POTENTIAL NUTRITIVE SUPPLEMENT IN CANCER
Naga Parpam is a Zinc Oxide based nano medicine, used in Siddha system. Physiochemical analysis is done for standardization of this medicine and to have knowledge of the working principle of this medicine. It has anticancer activity and it is seen in autoimmune diseases, there is a definite imbalance in the metals and in cancer, Zinc is depleted in cell level whereas it is accumulated in the blood plasma. Hence, for substitution of Zinc, it has to penetrate the cells and also it should be non-toxic, for which, Naga Parpam is considered. FTIR, SEM, EDAX, XRD and PL studies were done. The morphology shows that in Naga Parpam there are different sized particles, which falls in the nano size. This shows that this drug can penetrate at different penetration depths. Presence of Zinc, Oxygen, Silicon, Magnesium and Potassium has been established by EDAX studies. FTIR confirms the presence of ZnO, SiO2 and Mg. XRD confirms the presence of ZnO in hexagonal wurtzite structure. Secondary phase is seen, which is mainly due to Mg present in the sample. The broad peak at 525 nm, which is the characteristic peak for ZnO, from the PL studies also shows the disruption of structure due to the presence of Mg, which is also confirmed by the secondary phase in XRD. It is concluded that Naga Parpam is a potential candidate for substitution of Zn, in Zn depleted auto immune diseases and also in cancer.
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