{"title":"血浆胆碱酯酶活性。","authors":"R. Mirakhur","doi":"10.1097/00132586-198706000-00006","DOIUrl":null,"url":null,"abstract":"Plasma cholinesterase activity was estimated following administration of edrophonium 0.5 or 1.0 mg X kg-1 given for antagonism of atracurium-induced neuromuscular block. There was no inhibition of enzyme activity for up to three hours following edrophonium administration. This is in contrast to profound and prolonged inhibition of enzyme activity seen following neostigmine and pyridostigmine.","PeriodicalId":9371,"journal":{"name":"Canadian Anaesthetists' Society journal","volume":"97 1","pages":"588-90"},"PeriodicalIF":0.0000,"publicationDate":"1987-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"11","resultStr":"{\"title\":\"Edrophonium and plasma cholinesterase activity.\",\"authors\":\"R. Mirakhur\",\"doi\":\"10.1097/00132586-198706000-00006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Plasma cholinesterase activity was estimated following administration of edrophonium 0.5 or 1.0 mg X kg-1 given for antagonism of atracurium-induced neuromuscular block. There was no inhibition of enzyme activity for up to three hours following edrophonium administration. This is in contrast to profound and prolonged inhibition of enzyme activity seen following neostigmine and pyridostigmine.\",\"PeriodicalId\":9371,\"journal\":{\"name\":\"Canadian Anaesthetists' Society journal\",\"volume\":\"97 1\",\"pages\":\"588-90\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1987-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"11\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Canadian Anaesthetists' Society journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1097/00132586-198706000-00006\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Canadian Anaesthetists' Society journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/00132586-198706000-00006","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 11
摘要
血浆胆碱酯酶活性在给药0.5或1.0 mg X kg-1艾络芬用于对抗阿曲库利引起的神经肌肉阻滞后进行估计。给药后3小时内酶活性无抑制作用。这与新斯的明和吡哆斯的明对酶活性的深刻和长期抑制形成对比。
Plasma cholinesterase activity was estimated following administration of edrophonium 0.5 or 1.0 mg X kg-1 given for antagonism of atracurium-induced neuromuscular block. There was no inhibition of enzyme activity for up to three hours following edrophonium administration. This is in contrast to profound and prolonged inhibition of enzyme activity seen following neostigmine and pyridostigmine.
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