M. Hirahara, Masafumi Ogawa, M. Shigematsu, K. Nagayama, A. Satake, K. Hori, Itsumi Miyabe
{"title":"Ubidecarenone颗粒和细颗粒在光照下的稳定性和分解物质","authors":"M. Hirahara, Masafumi Ogawa, M. Shigematsu, K. Nagayama, A. Satake, K. Hori, Itsumi Miyabe","doi":"10.5649/JJPHCS1975.9.384","DOIUrl":null,"url":null,"abstract":"(Received May 20, 1983) A high performance liquid chromatograph (HPLC) was used for the quality test of Ubidecarenone (CoQ10) products. CoQ10 products were exposed to light under 2000 lux for 29 days, and their stability to light was studied with HPLC. The results were as follows: 1) Good separation of CoQ10. CoQ9 and UC9 was achieved with HPLC. 2) The amount of CoQ10 in granules and fine granules packed with Pile Packer Film was between 11% and 18% after 29day exposure to light, whereas CoQ10 in granules in lightshielded package and that in raw material powder packed with pile packer Film were 74% and 90%, respectively. 3) The main decomposition substance of the granules, the fine granules and raw material powder showed that the relative retention to CoQ10 was 0.49. Keywordsubidecarenone; ubichromenol9; quality test; stability to light","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"29 1","pages":"384-388"},"PeriodicalIF":0.0000,"publicationDate":"1983-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Stability and Decomposition Substances of Ubidecarenone Granules and Fine Granules on Exposure to Light\",\"authors\":\"M. Hirahara, Masafumi Ogawa, M. Shigematsu, K. Nagayama, A. Satake, K. Hori, Itsumi Miyabe\",\"doi\":\"10.5649/JJPHCS1975.9.384\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"(Received May 20, 1983) A high performance liquid chromatograph (HPLC) was used for the quality test of Ubidecarenone (CoQ10) products. CoQ10 products were exposed to light under 2000 lux for 29 days, and their stability to light was studied with HPLC. The results were as follows: 1) Good separation of CoQ10. CoQ9 and UC9 was achieved with HPLC. 2) The amount of CoQ10 in granules and fine granules packed with Pile Packer Film was between 11% and 18% after 29day exposure to light, whereas CoQ10 in granules in lightshielded package and that in raw material powder packed with pile packer Film were 74% and 90%, respectively. 3) The main decomposition substance of the granules, the fine granules and raw material powder showed that the relative retention to CoQ10 was 0.49. Keywordsubidecarenone; ubichromenol9; quality test; stability to light\",\"PeriodicalId\":17399,\"journal\":{\"name\":\"Journal of the Nippon Hospital Pharmacists Association\",\"volume\":\"29 1\",\"pages\":\"384-388\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1983-10-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the Nippon Hospital Pharmacists Association\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5649/JJPHCS1975.9.384\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Nippon Hospital Pharmacists Association","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5649/JJPHCS1975.9.384","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Stability and Decomposition Substances of Ubidecarenone Granules and Fine Granules on Exposure to Light
(Received May 20, 1983) A high performance liquid chromatograph (HPLC) was used for the quality test of Ubidecarenone (CoQ10) products. CoQ10 products were exposed to light under 2000 lux for 29 days, and their stability to light was studied with HPLC. The results were as follows: 1) Good separation of CoQ10. CoQ9 and UC9 was achieved with HPLC. 2) The amount of CoQ10 in granules and fine granules packed with Pile Packer Film was between 11% and 18% after 29day exposure to light, whereas CoQ10 in granules in lightshielded package and that in raw material powder packed with pile packer Film were 74% and 90%, respectively. 3) The main decomposition substance of the granules, the fine granules and raw material powder showed that the relative retention to CoQ10 was 0.49. Keywordsubidecarenone; ubichromenol9; quality test; stability to light
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
