关于患者安全:骨科医生必须停止对膝关节关节炎患者进行关节镜半月板部分切除术。

J. Rickert
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引用次数: 6

摘要

尽管对其疗效存在众所周知的担忧[12,13],但关节镜半月板部分切除术(APM)仍然是美国最常用的骨科手术之一[5]。这怎么可能呢?我认为,由于与APM相关的不良事件相对较少,骨科社区和我们的转诊医生将APM视为“面包和黄油”手术,通常是安全(和快速)的手术。此外,正如最近关于这一主题的临床对峙中所指出的[9],单个外科医生很容易认为这些证据不适用于他或她的患者或我们的结果——我们的患者在某种程度上是不同的。但最近的两项研究[1,4]对APM的严重长期风险敲响了警钟,并迫使我们减少对膝关节关节炎患者的使用,因为这样做实际上可能会使他们的健康状况恶化。第一项研究发现,与普通人群相比,接受APM并随访至少15年的患者进行膝关节置换术的可能性要高10倍[1]。这项研究的随访时间之长、规模之大(近100万患者)令人信服,其其他一些发现也令人信服,比如作者观察到,只有一个膝盖有APM病史的患者,膝关节置换术的风险是没有APM病史的患者的三倍。这项庞大的观察性研究[1]的发现得到了最近一项大型随机试验的有力支持,该试验得出了基本相同的结论[4]。这些作者发现,与非手术治疗的患者相比,通过膝关节镜治疗关节炎关节半月板撕裂的患者进行全膝关节置换术的可能性几乎是其5倍(同时没有更好的疼痛缓解)[4]。因此,从这些研究中得出的最明显的,实际上也是相当令人担忧的结论是,在膝关节关节炎患者中使用APM更有可能使他们接受后续的膝关节置换术。虽然对于许多经过合理的非手术治疗后症状仍然存在的患者来说,全膝关节置换术是一个很好的选择,但众所周知,该手术本身存在危及生命和肢体的风险[2]。使用像APM这样不能缓解症状的手术是错误的[3],但会增加我们的患者以后需要进行更大的膝关节置换术的机会[1,4]。我们做了太多的apm,证据清楚地表明这对我们的病人是有害的[1,4,11]。外科医生必须改变这种有害的做法。总编辑的注释:我们很高兴地介绍我们的下一期“患者安全”。Rickert博士是印第安纳大学医学院的临床教师,并担任the Society for Patient Centered Orthopedics的主席。本季度专栏的目标是通过参与不同的观点,包括骨科医生、患者、消费者和患者倡导者以及医疗保险公司,探索患者安全、价值和临床疗效之间的关系。我们欢迎读者对我们所有的专栏和文章进行反馈;请将您的意见发送至eic@clinorthop.org。提交人证明,他本人及其直系亲属均无任何可能与所提交文章产生利益冲突的商业协会(如咨询公司、股票所有权、股权、专利/许可安排等)。本文仅代表作者个人观点,不代表CORR或骨关节外科医师协会的观点或政策。J. Rickert MD (MD),印第安纳大学健康中心南印第安纳内科医生,Clarizz大道583号。,美国印第安纳州布卢明顿47401,电子邮件:jrickert1@iuhealth.org
本文章由计算机程序翻译,如有差异,请以英文原文为准。
On Patient Safety: Orthopaedic Surgeons Must Stop Performing Arthroscopic Partial Meniscectomy on Patients with Arthritic Knees.
Despite well-known concerns over its efficacy [12, 13], arthroscopic partial meniscectomy (APM) continues to be one of the most commonly performed orthopaedic procedures in the United States [5]. How can that be? I believe that because of the relative infrequency of adverse events related to APM, the orthopaedic community and our referring physicians view APM as a “bread-and-butter” operation that is a generally safe (and quick) procedure. Additionally, as noted in a recent Clinical Faceoff on this very topic [9], it is easy for an individual surgeon to believe that the evidence does not apply to his or her patients or our results—our patients are somehow different. But two recent studies [1, 4] sound the alarm on the serious longterm risks of APM and compel us to curtail its use in patients with arthritic knees as doing so may, in fact, worsen their health. The first of these studies found that patients who underwent APM and were followed for at least 15 years were 10 times more likely to proceed with a knee arthroplasty compared to the general population [1]. The length of this study’s follow-up, and its vast size (nearly 1 million patients) were compelling, as were a number of its other findings, such as the authors’ observation that patients with a history of APM in only one knee, the risk of knee arthroplasty was three times greater than in their knee without a history of APM. The findings of that enormous observational study [1] were substantially supported by a recent, large randomized trial that arrived at substantially the same conclusion [4]. Those authors found that patients treated with knee arthroscopy for meniscal tears in an arthritic joint were almost five times more likely to proceed to total knee replacement (while achieving no better pain relief) compared to those treated non-operatively [4]. Therefore, the most-obvious, and, indeed, quite alarming, conclusion from these studies is that the use of APM in patients with arthritic knees makes it more likely that they will undergo subsequent knee replacement. While total knee replacement is an excellent option for many patients whose symptoms persist despite reasonable non-surgical treatments, the operation carries well-known lifeand limb-threatening risks of its own [2]. It is wrong to use a procedure like APM that does not alleviate symptoms [3], but increases the chance that our patients will undergo even larger surgery later in the form of a knee replacement [1, 4]. Too many APMs are being done, and the evidence is clear that this is bad for our patients [1, 4, 11]. Surgeons must change this harmful practice A note from the Editor-in-Chief: We are pleased to present our next installment of “On Patient Safety.” Dr. Rickert is on the clinical faculty at Indiana University School of Medicine and serves as President of The Society for Patient Centered Orthopedics. The goal of this quarterly column is to explore the relationships among patient safety, value, and clinical efficacy by engaging with diverse perspectives, including those of orthopaedic surgeons, patients, consumer and patient advocates, and medical insurers. We welcome reader feedback on all of our columns and articles; please send your comments to eic@ clinorthop.org. The author certifies that neither he, nor any members of his immediate family, have any commercial associations (such as consultancies, stock ownership, equity interest, patent/licensing arrangements, etc.) that might pose a conflict of interest in connection with the submitted article. The opinions expressed are those of the writers, and do not reflect the opinion or policy of CORR or The Association of Bone and Joint Surgeons. J. Rickert MD (✉), IU Health Southern Indiana Physicians, 583 S Clarizz Blvd., Bloomington, IN, 47401 USA, Email: jrickert1@iuhealth.org
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