Elvira Hermawati, Suzanny Dwi Ellita, L. D. Juliawaty, E. Hakim
{"title":"对羟基苯甲酸和山奈酚的研究","authors":"Elvira Hermawati, Suzanny Dwi Ellita, L. D. Juliawaty, E. Hakim","doi":"10.26874/jkk.v3i1.51","DOIUrl":null,"url":null,"abstract":"Desmodium triquetrum (Fabaceae) is widely distributed in Indonesia and used as herbal medicines for diuretic, hemorrhoids, tonics, and anti-inflammatory. Two known compounds, p-hydroxybenzoic acid (1) and kaempferol (2), were isolated from the MeOH extract of the leaves of Desmodium triquetrum. The structures of isolated compounds were determined based on H and C NMR data. The MeOH extract showed very active with 6,5 μg/mL in addition, compound (1) and (2) showed weak cytotoxicity against murine cell leukemia P-388 with IC50 55,0 and 24,7 μg/mL, respectively. Compound (1) was the first reported in this species.","PeriodicalId":17768,"journal":{"name":"Jurnal Kartika Kimia","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"p-Hydroxybenzoic Acid and Kaempferol from\\nDesmodium triquetrum\",\"authors\":\"Elvira Hermawati, Suzanny Dwi Ellita, L. D. Juliawaty, E. Hakim\",\"doi\":\"10.26874/jkk.v3i1.51\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Desmodium triquetrum (Fabaceae) is widely distributed in Indonesia and used as herbal medicines for diuretic, hemorrhoids, tonics, and anti-inflammatory. Two known compounds, p-hydroxybenzoic acid (1) and kaempferol (2), were isolated from the MeOH extract of the leaves of Desmodium triquetrum. The structures of isolated compounds were determined based on H and C NMR data. The MeOH extract showed very active with 6,5 μg/mL in addition, compound (1) and (2) showed weak cytotoxicity against murine cell leukemia P-388 with IC50 55,0 and 24,7 μg/mL, respectively. Compound (1) was the first reported in this species.\",\"PeriodicalId\":17768,\"journal\":{\"name\":\"Jurnal Kartika Kimia\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-05-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Jurnal Kartika Kimia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.26874/jkk.v3i1.51\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jurnal Kartika Kimia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26874/jkk.v3i1.51","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
p-Hydroxybenzoic Acid and Kaempferol from
Desmodium triquetrum
Desmodium triquetrum (Fabaceae) is widely distributed in Indonesia and used as herbal medicines for diuretic, hemorrhoids, tonics, and anti-inflammatory. Two known compounds, p-hydroxybenzoic acid (1) and kaempferol (2), were isolated from the MeOH extract of the leaves of Desmodium triquetrum. The structures of isolated compounds were determined based on H and C NMR data. The MeOH extract showed very active with 6,5 μg/mL in addition, compound (1) and (2) showed weak cytotoxicity against murine cell leukemia P-388 with IC50 55,0 and 24,7 μg/mL, respectively. Compound (1) was the first reported in this species.