放射诱发脑膜瘤的严重病程——放射治疗后患者筛查的新见解?

Ł. Domagalski, J. Gałązka, P. Homa, Zofia Hoffman, Leon Sakwa, Michał Szymoniuk, M. Wdowiak, W. Czyżewski, K. Torres, R. Rola
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引用次数: 0

摘要

脑膜瘤多为良性肿瘤,起源于蛛网膜帽细胞。其发病机制是基于多种因素,包括过去的辐射。本文报告一位25岁的病人,他在急性淋巴细胞白血病期间因既往头部放射而发展为放射诱导的上矢状窦脑膜瘤。肿瘤的临床表现为头痛、恶心和头晕,随后进行计算机断层扫描和MRI检查。影像学检查显示一个非常广泛的、增强的肿瘤肿块位于两侧中央和上矢状窦内。由于诊断为矢状旁脑膜瘤的可能性最大,该患者符合切除肿瘤的条件。手术成功,实现了最大程度的安全次全切除。术后患者出现脑积水等并发症,住院5个月。本病例说明需要增加对受放射(包括放疗)威胁的患者的临床关注,重点关注可能的头部病变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Severe course of radiation-induced meningioma — a new insight in screening for patients after radiotherapy?
Meningiomas, being mostly benign tumours, are derived from the arachnoid cap cells. Their etiopatho - genesis is based on various factors, including past radiation. The presented case of a 25-year-old patient, who developed a radiation-induced superior sagittal sinus meningioma based on his past head radiation distributed during acute lymphocytic leukaemia. The tumour’s clinical image presented at first as head - ache, nausea, and dizziness, computer tomography and subsequently MRI were performed. The imaging examination revealed a very extensive, contrast-enhanced tumour mass located centrally on both sides and within the superior sagittal sinus. With the most likely diagnosis of parasagittal meningioma, the pa - tient was qualified for tumour excision. The surgery was performed successfully resulting in maximal safe subtotal resection. After the surgery, the patient developed complications including hydrocephalus, which resulted in 5-months long hospitalization. The presented case illustrated the need for increased clinical attention in patients threatened by radiation (including radiotherapy), focused on possible head lesions.
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