Optimization of the isolation of biologically active complexes from buds and shoots of birch and poplar buds for their further use in cosmeceutical compositions

The aim is to optimize the isolation of biologically active birch and poplar complexes based on woodworking industry waste to study their biological activity to create cosmeceutical compositions that have cosmetic and pharmaceutical effects. Materials and methods. The object of research is the vegetative organs of birch (buds and shoots) and poplar (buds). In the process of work, experimental studies were carried out on the extraction and separation of natural compounds, development of biological complexes of vegetative organs of birch and poplar, study of the chemical composition and standardization of biologically active complexes of birch and preparations based on them. Results. The optimal methods for extracting natural complexes were determined. Created as a semi-industrial installation for producing biologically active complexes by barothermal method, combining two processes - high pressure and hydrodistillation. The optimal operating cycle and plant parameters were determined. The optimal solvents for the extraction of biologically active complexes from the vegetative organs of birch and poplar have been determined. Petroleum ether (33.60 %) extracted the most compounds from birch buds, in birch shoots - ethanol (8.34 %). Qualitative and quantitative indicators of biologically active complexes are determined, and projects for examining the obtained biologically active complexes are proposed. We determined the yield of essential oil depending on the time of collection of raw materials and determined that the largest amount of essential oil is contained in spring buds (0.21 % of dry raw materials) and shoots (0.08 %). Conclusions. Biological complexes created from timber processing waste with high activity are the basis for the creation of cosmetic products. The created semi-industrial plant will provide the basis for creating new original products in industrial volumes.