Proceedings from the Canadian Society of Respiratory Therapists Annual Conference May 13–14, 2022

Background: The long-term impact of COVID-19 is still unknown. Objective: This study aimed to explore post COVID-19 effect on patients’ chest computed tomography (CT), lung function, respiratory symptoms, fatigue, functional capacity, health-related quality of life (HRQoL) and the ability to return to work beyond 3 months post-infection. Methods: A systematic search was performed on PubMed, Web of Science and Ovid MEDLINE on May 22, 2021, to identify studies that reported persistent effects of COVID-19 beyond 3 months follow-up. Data on the proportion of patients who had the outcome were collected and analyzed using a one-group meta-analysis. Results: Data were extracted from 24 articles that presented information on a total of 5323 post COVID-19 adults between 3 and 6 months after symptoms onset or hospital discharge. The pooled prevalence of CT abnormalities was 59% (95% CI 4473, I2 = 96%), abnormal lung function 39% (95% CI 24–55, I2 = 94%), fatigue 38% (95% CI 27–49, I2 = 98%), dyspnea 32% (95% CI 24–40, I2 = 98%), chest paint/tight-ness 16% (95% CI 12–21, I2 = 94%), and cough 13%, (95% CI 9–17, I2 = 94%). Decreased functional capacity and HRQoL were found in 36% (95% CI 22–49, I2 = 97%) and 52% (95% CI 33–71, they may be vaccine hesitant despite acknowledging that vaccination is necessary. This presentation will present an ethics methodology approach to encourage collaboration between opposing groups. Reasons for both vaccine hesitancy and vaccine support will be presented. The goal is to provide respiratory students and professionals with additional tools to approach vaccine-hesitant patients so that future confrontations are col-laborative and proactive. Recommended methods on how to approach and challenging patients on their values can help guide difficult discus-sions around vaccinations and mistrust in healthcare. The findings from this case series reveal that the pres-ence of ventilator-associated pneumonia in SARS-CoV-2 patients is a source of significant mortality. This study strengthens the importance of non-invasive mechanical ventilation strategies and also high-lights the need for careful infection control surveillance in invasive mechanical ventilation. Due to the high rates of VAP and associated increased mortality, uprating antibiotic/antifungal therapy selec-tion is also paramount in caring for SARS-CoV-2 cases admitted to the ICU. steps therapeutic algorithm for VV-ECMO ARDS 1. an optimization of mechanical ventilation before VV-ECMO consideration; 2. VV-ECMO indications; 3. start, maintenance and weaning phases of VV-ECMO; 4. post decannulation. The complex interaction between a patient, a VV-ECMO machine, and a mechanical ventilator as well as challenges of respiratory monitoring be