Bactobilia Among Patients with Uncomplicated Cholelithiasis Undergoing Laparoscopic Cholecystectomy: The Risk Factors and Effects on Postoperative Infectious Complications

Background: Determining the rate of bactibilia among patients under going laparoscopic cholecystectomy (LC) and its correla-tions with predisposing factors and postoperative infections, which help evaluate the need for prophylactic antibiotic. Methods: In this prospective study, 85 consecutive patients with uncomplicated cholelithiasis who underwent LC were enrolled from2012to2013. Routinebileculturewasdoneatthetimeof LC.Patientsweredividedinto2groups,1withnegativebilecultureand anotherwithbactibilia. Demographicandlaboratorydatawerecompared. Patientswerefollowedup10daysaftertheirlaparoscopy and 1 month after discharge to monitor the presence of infection. Results: Atotalof 7culturesof bilewerepositiveforbacteria(8.2%). Thepatients’ agewasthesolefactorwithasignificantrelation-ship with the rate of bactobilia (P = 0.016). Within 10 days after surgery, fever and surgical site infection were detected in 10.6% of patients, which was not significantly different in the 2 groups. There were no complications in the 30-day follow-up. Conclusions: Detectingbactobiliawithlowfrequencyandthelackof correlationbetweenbactobiliaandpostoperativeinfectious, complications did not support prescribing prophylactic antibiotic in respective patients. The older age was the sole predisposing factor for the development of bactobilia.