纳米给药系统用于癌症治疗:新一代治疗技术

Prabu Sl
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引用次数: 0

摘要

尽管肿瘤的创新治疗方法取得了显著进展,但癌症仍被认为是导致疾病和死亡的主要原因之一,其病理生理非常复杂。对于癌症患者来说,治疗特性和全球生存率仍然令人失望。这些癌症治疗的能力不足,因此制定了一些新的战略,以提供更好的治疗方法,以提高他们的生活质量,并有助于减少死亡人数。在确保理想的癌症管理的主要阶段是早期诊断和靶向药物输送抗肿瘤以减少其毒性。近年来,纳米技术作为一种新的治疗方法,已经取得了进展,并试图克服以前可用于癌症治疗的药物输送系统的许多限制。纳米治疗提供了直接接触肿瘤细胞的机会,改善了药物定位、细胞应用以及提供靶向药物递送,避免了与健康细胞的相互作用。本文综述了各种新型纳米材料作为抗肿瘤药物载体在肿瘤治疗中的应用;同时提供纳米技术在癌症治疗中的最高必要性及其在靶向药物递送方面的挑战
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nano based Drug Delivery System for Cancer Therapy: A Next Generation Theranostics
Cancer is considered as one of the foremost cause of illness and death with very complex pathophysiology even though prominent advancement has been made on innovative tumor treatments. Therapeutic properties and the global survival rate are still disappointing for the patients with cancer. There is a shortfall in the capabilities of these cancer therapies, some novel strategies are developed to provide better treatment therapies to improve their quality of life and also aids in reducing the number of deaths. Amongst the cardinal phases towards ensuring ideal cancer management is early diagnosis and targeted drug delivery of anti-tumor to decrease its toxicities. Recently the progress of nanotechnology as novel therapeutics, have advanced and trialed to overwhelm numerous limitations of previously available drug delivery systems for cancer treatment. Nanobased therapeutics has provided the chance to directly contact the tumorous cells selectively with improved drug localization, cellular application as well as providing targeted drug delivery eluding the interaction with the healthy cells. In this review, we summarize about various novel nanomaterials as anti-tumour drug delivery carriers for cancer treatment; also provide insight into the superlative necessities of nanotechnology in cancer therapy and its challenges in targeted drug delivery
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