Soraia Rodrigues , Vanessa Metrogos , Marco Dores , José João Marques , Miguel Rodrigues , Miguel Cabrita , Gilberto Rosa , Aníbal Coutinho
{"title":"睾丸肿瘤的保守手术","authors":"Soraia Rodrigues , Vanessa Metrogos , Marco Dores , José João Marques , Miguel Rodrigues , Miguel Cabrita , Gilberto Rosa , Aníbal Coutinho","doi":"10.1016/j.acup.2016.01.001","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>Malignant germ cell tumors represent the majority of testicular masses; according to current knowledge, radical orchiectomy remains the standard of care in the management of this type of cancer. However, testis‐sparing surgery (TSS) can be an alternative to radical surgery in selected cases, particularly in patients with small testicular masses (STM).</p></div><div><h3>Objective</h3><p>The authors conducted a review of the current indications for performing testicular sparing surgery as well as functional and oncological results of it.</p></div><div><h3>Material and methods</h3><p>We conducted a literature search in Medline database (PubMed) using the keywords: “testis sparing surgery”, “partial orchiectomy”, ‘testis tumor’, ‘small testicular mass/tumor’. The search was limited to article in English language, published from 2010 to the current date.</p></div><div><h3>Results</h3><p>randomized controlled trials/studies with high level of evidence that compare TSS with radical orchiectomy were not found. Indications for TSS are still controversial, particularly in patients with normal contralateral testis. The organ sparing surgery seems a viable therapeutic option for patients with small non‐palpable testicular mass (with <<!--> <!-->20<!--> <!-->mm major axis), bilateral tumors or single testicle. The frozen section examination plays a decisive role in the technique, since it allows the distinction between malignant and benign neoplasms, as well as assessing the status of surgical margins. The medium and long follow‐up results of the analyzed retrospective studies revealed no significant risk of local and/or distant relapses.</p></div><div><h3>Conclusion</h3><p>Regarding the testis, the organ‐sparing surgery can be adopted safely in the treatment of selected cases. Prospective multicentric and high level of evidence studies are needed in order for TSS become a real alternative to radical surgery, as well to evaluate the oncological safety and real functional benefits of preserving the testis.</p></div>","PeriodicalId":100020,"journal":{"name":"Acta Urológica Portuguesa","volume":"33 1","pages":"Pages 22-27"},"PeriodicalIF":0.0000,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.acup.2016.01.001","citationCount":"0","resultStr":"{\"title\":\"Cirurgia conservadora nos tumores do testículo\",\"authors\":\"Soraia Rodrigues , Vanessa Metrogos , Marco Dores , José João Marques , Miguel Rodrigues , Miguel Cabrita , Gilberto Rosa , Aníbal Coutinho\",\"doi\":\"10.1016/j.acup.2016.01.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><p>Malignant germ cell tumors represent the majority of testicular masses; according to current knowledge, radical orchiectomy remains the standard of care in the management of this type of cancer. However, testis‐sparing surgery (TSS) can be an alternative to radical surgery in selected cases, particularly in patients with small testicular masses (STM).</p></div><div><h3>Objective</h3><p>The authors conducted a review of the current indications for performing testicular sparing surgery as well as functional and oncological results of it.</p></div><div><h3>Material and methods</h3><p>We conducted a literature search in Medline database (PubMed) using the keywords: “testis sparing surgery”, “partial orchiectomy”, ‘testis tumor’, ‘small testicular mass/tumor’. The search was limited to article in English language, published from 2010 to the current date.</p></div><div><h3>Results</h3><p>randomized controlled trials/studies with high level of evidence that compare TSS with radical orchiectomy were not found. Indications for TSS are still controversial, particularly in patients with normal contralateral testis. The organ sparing surgery seems a viable therapeutic option for patients with small non‐palpable testicular mass (with <<!--> <!-->20<!--> <!-->mm major axis), bilateral tumors or single testicle. The frozen section examination plays a decisive role in the technique, since it allows the distinction between malignant and benign neoplasms, as well as assessing the status of surgical margins. The medium and long follow‐up results of the analyzed retrospective studies revealed no significant risk of local and/or distant relapses.</p></div><div><h3>Conclusion</h3><p>Regarding the testis, the organ‐sparing surgery can be adopted safely in the treatment of selected cases. Prospective multicentric and high level of evidence studies are needed in order for TSS become a real alternative to radical surgery, as well to evaluate the oncological safety and real functional benefits of preserving the testis.</p></div>\",\"PeriodicalId\":100020,\"journal\":{\"name\":\"Acta Urológica Portuguesa\",\"volume\":\"33 1\",\"pages\":\"Pages 22-27\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.acup.2016.01.001\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta Urológica Portuguesa\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2341402216000021\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Urológica Portuguesa","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2341402216000021","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Malignant germ cell tumors represent the majority of testicular masses; according to current knowledge, radical orchiectomy remains the standard of care in the management of this type of cancer. However, testis‐sparing surgery (TSS) can be an alternative to radical surgery in selected cases, particularly in patients with small testicular masses (STM).
Objective
The authors conducted a review of the current indications for performing testicular sparing surgery as well as functional and oncological results of it.
Material and methods
We conducted a literature search in Medline database (PubMed) using the keywords: “testis sparing surgery”, “partial orchiectomy”, ‘testis tumor’, ‘small testicular mass/tumor’. The search was limited to article in English language, published from 2010 to the current date.
Results
randomized controlled trials/studies with high level of evidence that compare TSS with radical orchiectomy were not found. Indications for TSS are still controversial, particularly in patients with normal contralateral testis. The organ sparing surgery seems a viable therapeutic option for patients with small non‐palpable testicular mass (with < 20 mm major axis), bilateral tumors or single testicle. The frozen section examination plays a decisive role in the technique, since it allows the distinction between malignant and benign neoplasms, as well as assessing the status of surgical margins. The medium and long follow‐up results of the analyzed retrospective studies revealed no significant risk of local and/or distant relapses.
Conclusion
Regarding the testis, the organ‐sparing surgery can be adopted safely in the treatment of selected cases. Prospective multicentric and high level of evidence studies are needed in order for TSS become a real alternative to radical surgery, as well to evaluate the oncological safety and real functional benefits of preserving the testis.