{"title":"外泌体生物学特性及其在肝癌中的作用研究 Biological Characteristics of Exosomes and Their Role in Hepatocellular Carcinoma","authors":"张腾飞, 黄修燕","doi":"10.12677/WJCR.2018.81003","DOIUrl":null,"url":null,"abstract":"肝细胞癌(HCC)发生发展的分子机制尚未完全清楚，可能涉及病毒致癌作用、癌基因和抑癌基因失活、癌细胞凋亡等。外泌体能介导细胞间物质传递和信息交流，在多种癌症发生发展中起着重要作用。本文旨在总结外泌体生物学特性及其在肝癌发生发展、诊断和治疗中的作用。 The mechanism of hepatocellular carcinoma (HCC) development is not yet fully understood, which may be related to the carcinogenesis of the virus, the inactivation of oncogenes and tumor sup-pressor genes, cancer cell apoptosis. Exosomes, which can mediate the material transfer between cells and the exchange of information, play significant roles in the occurrence and development of a variety of cancers. This article aims to summarize the biological characteristics of exosomes and their roles in the development, diagnosis and treatment of HCC.","PeriodicalId":22619,"journal":{"name":"The Journal of Cancer Research","volume":"43 1","pages":"12-17"},"PeriodicalIF":0.0000,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"外泌体生物学特性及其在肝癌中的作用研究 Biological Characteristics of Exosomes and Their Role in Hepatocellular Carcinoma\",\"authors\":\"张腾飞, 黄修燕\",\"doi\":\"10.12677/WJCR.2018.81003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"肝细胞癌(HCC)发生发展的分子机制尚未完全清楚，可能涉及病毒致癌作用、癌基因和抑癌基因失活、癌细胞凋亡等。外泌体能介导细胞间物质传递和信息交流，在多种癌症发生发展中起着重要作用。本文旨在总结外泌体生物学特性及其在肝癌发生发展、诊断和治疗中的作用。 The mechanism of hepatocellular carcinoma (HCC) development is not yet fully understood, which may be related to the carcinogenesis of the virus, the inactivation of oncogenes and tumor sup-pressor genes, cancer cell apoptosis. Exosomes, which can mediate the material transfer between cells and the exchange of information, play significant roles in the occurrence and development of a variety of cancers. This article aims to summarize the biological characteristics of exosomes and their roles in the development, diagnosis and treatment of HCC.\",\"PeriodicalId\":22619,\"journal\":{\"name\":\"The Journal of Cancer Research\",\"volume\":\"43 1\",\"pages\":\"12-17\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Journal of Cancer Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.12677/WJCR.2018.81003\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Cancer Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12677/WJCR.2018.81003","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
肝细胞癌(HCC)发生发展的分子机制尚未完全清楚，可能涉及病毒致癌作用、癌基因和抑癌基因失活、癌细胞凋亡等。外泌体能介导细胞间物质传递和信息交流，在多种癌症发生发展中起着重要作用。本文旨在总结外泌体生物学特性及其在肝癌发生发展、诊断和治疗中的作用。 The mechanism of hepatocellular carcinoma (HCC) development is not yet fully understood, which may be related to the carcinogenesis of the virus, the inactivation of oncogenes and tumor sup-pressor genes, cancer cell apoptosis. Exosomes, which can mediate the material transfer between cells and the exchange of information, play significant roles in the occurrence and development of a variety of cancers. This article aims to summarize the biological characteristics of exosomes and their roles in the development, diagnosis and treatment of HCC.
外泌体生物学特性及其在肝癌中的作用研究 Biological Characteristics of Exosomes and Their Role in Hepatocellular Carcinoma
肝细胞癌(HCC)发生发展的分子机制尚未完全清楚，可能涉及病毒致癌作用、癌基因和抑癌基因失活、癌细胞凋亡等。外泌体能介导细胞间物质传递和信息交流，在多种癌症发生发展中起着重要作用。本文旨在总结外泌体生物学特性及其在肝癌发生发展、诊断和治疗中的作用。 The mechanism of hepatocellular carcinoma (HCC) development is not yet fully understood, which may be related to the carcinogenesis of the virus, the inactivation of oncogenes and tumor sup-pressor genes, cancer cell apoptosis. Exosomes, which can mediate the material transfer between cells and the exchange of information, play significant roles in the occurrence and development of a variety of cancers. This article aims to summarize the biological characteristics of exosomes and their roles in the development, diagnosis and treatment of HCC.
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