双引物癌:恶性叶状瘤和浸润性导管癌1例报告

Lauraine Wijayaningtyas Sinuraya, K. Y. Yarso
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摘要

导读:在乳腺癌患者中有多原发灶的报道,发生率在4.1%至16.4%之间。本报告遵循标准外科病例报告(SCARE)并讨论了两种组织学上不同的乳腺癌恶性肿瘤。本文还探讨了多发原发恶性肿瘤的危险因素、发病机制、治疗及预后。病例介绍:患者是一名45岁的女性,左乳房和右乳房肿块五年。病人声称肿块变大了,但无痛。左乳肿瘤大小3 × 2 × 3cm,右乳肿瘤大小4 × 2 × 4cm,患者未见淋巴结肿大。左乳活检显示浸润性导管癌NST(无特殊类型)3级,LV1(+)。右乳活检示恶性叶状瘤。因此,患者必须接受化疗和乳房切除术作为最终治疗。该患者已完成治疗,目前正在接受评估。结论:本报告寻找罕见的乳房双原发恶性肿瘤病例。它强调了双原发癌最近开始增加,但以一种特殊的方式,因为它发生在同一个器官,乳房。然而,医学文献很少出现同步恶性肿瘤病例,促使该病例的发表。随着癌症治疗的改善和生存期的延长,双重癌症患者的数量正在增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Case Report of Double Primer Cancer: Malignant Phyllodes Tumor and Invasive Ductal Carcinoma
Introduction: Multiple primaries have been reported in patients with breast cancer in the range of 4.1% to 16.4%. This report followed the standard Surgical Case Report (SCARE) and discussed two histologically distinct breast cancer malignancies. This paper also explored the risk factor, pathogenesis, treatment, and prognosis of multiple primary malignancies in the same organs, especially in the breasts.Case Presentation: The patient was a 45-year-old woman with a lump in the left and right breasts for five years. The patient claimed that the lump was enlarged and painless. The tumor size of the left breast was 3 x 2 x 3 cm, the right breast was 4 x 2 x 4 cm, and the patient had no enlargement of lymph nodes. The patient underwent a biopsy examination of the left breast showing invasive ductal carcinoma NST (No Special Type) 3rd grade with LV1 (+). The biopsy examination of the right breast showed malignant phyllodes tumor. Thus, the patient must undergo chemotherapy and mastectomy as definitive therapy. The patient has already completed the treatment and is currently under evaluation.Conclusion: This report looked for the rare case of double primary malignancies in the breasts. It highlighted double primary cancers starting to increase these days but in a particular way because it happens in the same organ, the breasts. However, medical literature rarely presented a synchronous malignancy case, prompting the publishing of this case. With improved cancer treatment and more prolonged survival, the number of patients with double cancers is increasing.
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