大麻二酚与非甾体抗炎药物相互作用:1例药物性无菌性脑膜炎

M. Emig, Jafar Kafaie, Samantha K Ong, Xujian Li
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引用次数: 1

摘要

在医学界,人们越来越广泛地使用大麻二酚(CBD)和其他大麻衍生物来缓解各种症状。虽然这些产品已经显示出其镇痛特性的希望,但对这些药物和其他药物的潜在药理相互作用知之甚少。我们报告一位57岁的白人女性,她表现为精神状态改变、共济失调、左侧麻木和言语不清。广泛的检查完成后,发现基本没有异常,但详细的病史显示,患者的症状可能是由同时使用CBD和非甾体抗炎药(NSAIDs)引起的,导致药物性无菌性脑膜炎。CBD的良性性质使其成为缓解疼痛的有希望的途径。医生和患者应该被告知CBD和其他药物的潜在药物相互作用。中华神经科学杂志,2020;10(4):132-135 doi: https://doi.org/10.14740/jnr598
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cannabidiol and Non-Steroidal Anti-Inflammatory Drug Interactions: A Case of Drug-Induced Aseptic Meningitis
Cannabidiol (CBD) and other marijuana derivatives are being more widely used in the medical community by people in an attempt to alleviate a variety of symptoms. While these products have shown promise in their analgesic properties, little is known about the potential pharmacological interactions of these and other drugs. We present a case of a 57-year-old Caucasian woman who presented with altered mental status, ataxia, left-sided numbness, and slurred speech. An extensive workup was completed and found to be largely unremarkable, though a thorough history revealed that her symptoms were likely caused by concurrent use of CBD and non-steroidal anti-inflammatory drugs (NSAIDs) resulting in drug-induced aseptic meningitis. The benign nature of CBD makes it a promising avenue for pain relief. Physicians and patients should be informed about the potential drug-drug interactions of CBD and other medications. J Neurol Res. 2020;10(4):132-135 doi: https://doi.org/10.14740/jnr598
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