正常小鼠脑磁共振血管造影研究，用于创建三维脑血管图谱和标记血管的软件

2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW) Pub Date : 2011-11-12 DOI:10.1109/BIBMW.2011.6112522

Rajeshree Joshi, N. Yanasak

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引用次数: 2

摘要

在我们的实验室，我们正在研究遗传性出血性毛细血管扩张(HHT)的小鼠模型，这是一种导致大脑动静脉畸形(AVMs)的遗传疾病。利用该小鼠模型和磁共振血管成像(MRA)技术，我们正在追求跟踪动静脉畸形的目标，以确定一个通过纵向进化对动静脉畸形分层的分类系统。在这项工作开始之前，我们需要建立一个健康正常小鼠大脑的三维(3D) MRA图谱进行比较。我们所建立的三维图谱利用图形化软件工具呈现了健康正常小鼠大脑的血管结构。

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Magnetic resonance angiography study of a normal mouse brain for creating a three-dimensional cerebral vasculature atlas and software for labeling vessels

In our lab, we are studying a mouse model of Hereditary Hemorrhagic Telangiectasia (HHT), a genetic disorder that leads to ArterioVenous Malformations (AVMs) in brain. Using this mouse model and the technique of Magnetic Resonance Angiography (MRA), we are pursuing the goal of tracking AVMs to determine a classification system that stratifies AVMs by longitudinal evolution. Before this work can occur, we need to build a three-dimensional (3D) MRA Atlas for a healthy normal mouse brain for comparison. The 3D atlas we have built presents the vascular structure for the healthy normal mouse brain using a graphical software tool.

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2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW)

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