H. Viinamäki, H. Koivumaa-Honkanen, K. Honkalampi, K. Haatainen, T. Tolmunen, R. Antikainen, J. Hintikka
{"title":"绝望、低社会和职业功能与抑郁症无法康复相关——一项6年随访研究的结果","authors":"H. Viinamäki, H. Koivumaa-Honkanen, K. Honkalampi, K. Haatainen, T. Tolmunen, R. Antikainen, J. Hintikka","doi":"10.4137/CMPsy.S768","DOIUrl":null,"url":null,"abstract":"Objective The aim of this study was to explore variables associated with poor recovery from depression. Method A sample of depressive patients (n = 121) referred to treatment was followed prospectively for 6 years. Clinical evaluations were done at baseline and at 6 month, 1, 2 and 6 years study visits. A diagnosis of major depression based on SCID interview at 6 year and high BDI score along follow-up indicated poor recovery. A diagnosis of full remission at 6 year and low BDI score during follow-up indicated good recovery. Results Chronic depression was found in 15% of patients. A repeated measures analysis of variance of HDRS-, SCL-90, hopelessness (HS) and Social and Occupational Functioning Assessment Scale (SOFAS) scores showed that those with poor recovery had recovered poorly also according these scales during the whole follow-up. Treatment factors did not associate with recovery. Logistic regression analyses revealed an independent association between poor recovery at 6 year and both high HS- and low SOFAS scores at 12 months, 24 months and 6 year assessments. Conclusions Assessment of hopelessness and social and occupational functioning help to early identify high-risk patients who would be in need for more individually tailored treatments.","PeriodicalId":10437,"journal":{"name":"Clinical Medicine Insights: Psychiatry","volume":"23 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Hopelessness and Low Social and Occupational Functioning are Associated with Non-Recovery from Depression—Results of a 6-Year Follow-Up Study\",\"authors\":\"H. Viinamäki, H. Koivumaa-Honkanen, K. Honkalampi, K. Haatainen, T. Tolmunen, R. Antikainen, J. Hintikka\",\"doi\":\"10.4137/CMPsy.S768\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective The aim of this study was to explore variables associated with poor recovery from depression. Method A sample of depressive patients (n = 121) referred to treatment was followed prospectively for 6 years. Clinical evaluations were done at baseline and at 6 month, 1, 2 and 6 years study visits. A diagnosis of major depression based on SCID interview at 6 year and high BDI score along follow-up indicated poor recovery. A diagnosis of full remission at 6 year and low BDI score during follow-up indicated good recovery. Results Chronic depression was found in 15% of patients. A repeated measures analysis of variance of HDRS-, SCL-90, hopelessness (HS) and Social and Occupational Functioning Assessment Scale (SOFAS) scores showed that those with poor recovery had recovered poorly also according these scales during the whole follow-up. Treatment factors did not associate with recovery. Logistic regression analyses revealed an independent association between poor recovery at 6 year and both high HS- and low SOFAS scores at 12 months, 24 months and 6 year assessments. Conclusions Assessment of hopelessness and social and occupational functioning help to early identify high-risk patients who would be in need for more individually tailored treatments.\",\"PeriodicalId\":10437,\"journal\":{\"name\":\"Clinical Medicine Insights: Psychiatry\",\"volume\":\"23 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2008-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Medicine Insights: Psychiatry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4137/CMPsy.S768\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Medicine Insights: Psychiatry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4137/CMPsy.S768","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Hopelessness and Low Social and Occupational Functioning are Associated with Non-Recovery from Depression—Results of a 6-Year Follow-Up Study
Objective The aim of this study was to explore variables associated with poor recovery from depression. Method A sample of depressive patients (n = 121) referred to treatment was followed prospectively for 6 years. Clinical evaluations were done at baseline and at 6 month, 1, 2 and 6 years study visits. A diagnosis of major depression based on SCID interview at 6 year and high BDI score along follow-up indicated poor recovery. A diagnosis of full remission at 6 year and low BDI score during follow-up indicated good recovery. Results Chronic depression was found in 15% of patients. A repeated measures analysis of variance of HDRS-, SCL-90, hopelessness (HS) and Social and Occupational Functioning Assessment Scale (SOFAS) scores showed that those with poor recovery had recovered poorly also according these scales during the whole follow-up. Treatment factors did not associate with recovery. Logistic regression analyses revealed an independent association between poor recovery at 6 year and both high HS- and low SOFAS scores at 12 months, 24 months and 6 year assessments. Conclusions Assessment of hopelessness and social and occupational functioning help to early identify high-risk patients who would be in need for more individually tailored treatments.