阿苯达唑和左旋咪唑对鱼类肠道寄生虫的影响

R. Mowafy, H. Megahed, Sarah A. A. Ibrahim, S. Salim, Abd-Allah S. Hamed, H. Salah, Soad Mekawy
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引用次数: 0

摘要

不断寻找更有效的治疗策略和药物来克服鱼类肠道寄生虫是在耐药的背景下开展这项研究的动机,因为尼罗鱼和克拉丽亚鱼的寄生虫多样性导致了经济问题。采用了两个阶段来评价最常用的驱虫药阿苯达唑和左旋咪唑的治疗效果。第一阶段对部分养殖场的320条鱼进行了内寄生虫调查。对鱼粪便进行寄生虫学检查,包括体格检查和临床症状。对以往检出阳性病例的50只阳性鱼进行了病理和寄生虫学调查。将66条第一阶段感染的鱼与未感染的鱼进行分组,将其运送到第二阶段进行实验。对实验鱼进行了全面的病理、血液学和生化研究。第一阶段共检出阳性116例,肠道寄生虫感染率为36.25%(116/320)。从50尾解剖鱼中分离出5种寄生虫,分别为囊虫、线虫和吸虫。第二阶段结果显示,治疗组明显改善,两种抗寄生虫药物的结果几乎相似。介绍了完整的病理、血液学和生化检查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of applying albendazole and Levamisole against some intestinal parasites in fish
T he continuous search for more effective therapeutic strategies and drugs to overcome the fishs' intestinal parasites was an incentive to carry out this study in the context of drug resistance and because of parasitic diversity in both Oreochromis niloticus and Clarias garpeinus leading to economic problems. Two stages have been implemented to evaluate the therapeutic effect of the most used anthelmintic drugs albendazole, and levamisole. The survey of some fish farms for internal parasites was applied on 320 fish as a first stage. The parasitological examinations were applied on fish fecal matter including physical examination and clinical signs. pathological investigation in companion with parasitological one was executed on 50 positive fish obtained from positive cases previously examined. Sixty-six infected fish from first stage were transported to the second stage which is experimental by divided it into groups compared with non-infected fish. Full pathological, hematological and biochemical studies on experimental fish were executed. Our results of first stage were exhibited total-ly116 positive cases with prevalence (116/320) 36.25% of infestation with intestinal parasites. Five helminth parasites represented by cestode, nematode and trematode were isolated from total 50 dissected fish. The results of second stage were in favor of the treated groups showed marked improvement while both antiparasitic drugs revealed nearly similar results. Full pathological, hematological and biochemical studies were introduced.
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