一项随机单盲对比实验研究,探讨脊髓麻醉下剖宫产术中静脉输液时机对产妇血流动力学的影响

Sinchu Mary Babu, Geo Navin Jude, R. Devaprasath
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引用次数: 0

摘要

脊髓麻醉引起的低血压可以通过几种技术和方法预防,这是非常重要的,因为母亲和胎儿的生命处于危险之中。本研究比较了脊髓麻醉前6小时和半小时晶体给药降低低血压的效果。在获得知情同意后,选择110例年龄在20 ~ 40岁的ASA 2型患者在脊髓麻醉下行选择性下节段剖宫产术。患者被随机分为两组。第一组:参与者每晚口服零剂量,在手术前半小时给予乳酸林格氏盐。第二组:给予乳酸林格酯。剂量根据Holiday Segar公式(前10 kg为4ml/kg, 10-20 kg- 2ml/kg,其余为1ml /kg),两组分别在半小时和6小时内稳定给予。记录两组患者低血压的发生率和救助性升压药物的使用情况。两组在年龄、身高和体重方面具有统计学上的可比性。第1组低血压发生率为12.7%,第2组为25%,差异无统计学意义。1组55例患者中有7例收缩压比基线值<20%,而2组55例患者中有14例收缩压比基线值<20%,差异无统计学意义。两组患者使用麻黄素的发生率均无统计学意义。本研究结果显示,术前6小时或半小时补液在预防低血压方面无统计学差异。因此,为了提供预负荷的液体,没有必要延迟手术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A randomized single-blinded comparative experimental study to test the influence of timing of intravenous fluid therapy on maternal hemodynamics during lower segmental caesarean section under spinal anaesthesia
: Spinal anaesthesia-induced hypotension can be prevented by several techniques and methodologies, which is very important as the life of the mother and fetus is at risk. This study compared the efficacy of crystalloid administration 6 hours and half an hour before spinal anaesthesia on reducing hypotension.: After obtaining informed consent, 110 ASA 2 patients aged between 20 and 40 were scheduled for elective lower segmental caesarean section under spinal anaesthesia. Patients were randomly allocated into two groups. Group 1: Participants were kept nil per oral overnight, and Ringer's lactate was administered over half an hour before surgery. Group 2: participants were given ringer lactate. The amount was based upon the Holiday Segar formula (first 10 kg received 4ml/kg, 10-20 kg- 2ml/kg and remaining received 1 ml/kg) and given steadily over half an hour and 6 hours respectively in both groups. The incidence of hypotension and the need for rescue vasopressor in the two groups was recorded.: The two groups were statistically comparable in terms of age, height and weight. The incidence of Hypotension in Group 1 was 12.7%, and in Group 2 was 25%, which was statistically insignificant. Seven out of 55 patients in Group 1 had SBP<20% from baseline, whereas in Group 2, 14 patients out of 55 patients had SBP <20% from baseline, which was statistically insignificant. The incidence of ephedrine usage was statistically insignificant in both groups.: This study's results showed no statistically significant difference in preventing hypotension whether the fluids were given as 6 hours or half an hour before surgery. Therefore, to deliver preload of fluid, it is unnecessary to delay surgery.
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