CORR Insights®:脊柱后凸切除术是否能改善脊髓脊膜膨出患者的生活质量?

R. El-Hawary
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引用次数: 0

摘要

脊髓脊膜膨出患者的后凸可引起皮肤溃疡、疼痛和坐姿严重不平衡。支具可以稳定畸形或延迟手术干预,直到骨骼成熟,但并不总是有效的。手术指征包括覆盖在gibbus上的软组织包膜破裂,矢状面失衡和进行性畸形。这种情况很难手术治疗,因为并发症,如矫形丧失、固定丧失、翻修手术,甚至术后死亡是令人不安的常见[1- 3,5,6,8 -11]。伤口愈合和感染是再手术的常见原因,可能是通过脊髓脊膜膨出患者的脆弱软组织疤痕进行手术的结果。通过避免软组织瘢痕的切口,Hyndman的Halifax后凸切除术和Torode的技术可以降低伤口愈合问题的风险[3,12],但并不能完全消除这种风险。虽然椎弓根螺钉固定在一定程度上缓解了这些问题,但由于后路元素的解剖缺陷和骨质量差,可能会导致固定丢失[1,5]。在目前的研究中,Petersen等[9]评估了脊髓脊膜膨出患儿行腰椎后凸矫正手术后并发症和再手术的风险,以及手术对健康相关生活质量(HRQoL)的影响。他们的技术包括通过S1椎间孔插入“s形”椎棒和胸椎椎弓根螺钉进行后路固定。作者发现并发症(包括需要进行体外移植术的感染和需要进行推进皮瓣覆盖的伤口破裂)很常见,68%的患者再次手术[9]。他们的研究支持了其他几个记录了该患者群体并发症和再手术高风险的研究[2,8,10]。本研究的结果很重要,因为作者评估了接受后椎体切除术患者的HRQoL[9]。虽然以前的研究只关注手术结果,但目前的研究侧重于从患者的角度来看结果。由于他们报告了HRQoL的改善,尽管并发症发生率很高,但他们的研究结果使临床医生能够更自信地向患者咨询手术的潜在影响[9]。患者预计将来可能会有计划外的再手术,但他们的生活质量仍应得到改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
CORR Insights®: Does Kyphectomy Improve the Quality of Life of Patients With Myelomeningocele?
Kyphosis in patients with myelomeningocele can cause skin ulceration, pain, and substantial sitting imbalance. Bracing may stabilize the deformity or delay surgical intervention until skeletal maturity, but it is not always effective. Surgical indications include breakdown of the soft-tissue envelope overlying the gibbus, sagittal imbalance, and progressive deformity. This condition is difficult to treat surgically because complications, such as loss of correction, loss of fixation, revision surgery, and even death after surgery are disconcertingly common [1-3, 5, 6, 8-11]. Wound healing and infection are common reasons for reoperation in this population and are likely a result of operating through the tenuous soft-tissue scar of patients with myelomeningocele. By avoiding incisions through the soft-tissue scar, Hyndman’s Halifax kyphectomy and Torode’s technique may decrease the risk of wound-healing problems [3, 12], but they do not eliminate it. Loss of fixation may be caused by anatomic deficiency of the posterior elements and poor bone quality, though pedicle screw fixation has demonstrated some promise in mitigating these issues [1, 5]. In the current study, Petersen and colleagues [9] evaluated the risk of complications and reoperation as well as the impact of surgery on healthrelated quality of life (HRQoL) in children with myelomeningocele undergoing surgical correction of their lumbar kyphosis. Their technique involves posterior fixation using "Sshaped" rods inserted through the foramina of S1 and pedicle screws in the thoracic spine. The authors found that complications (including infection requiring débridement and wound breakdown requiring plastic surgery with advancement flap for coverage) were common and 68% of the patients underwent reoperation [9]. Their study supports several others that have documented a high risk of complications and reoperations in this patient population [2, 8, 10]. The results in the current study are important because the authors evaluated HRQoL in patients treated with kypectomy [9]. While previous studies have focused on surgical outcomes alone, the current study focuses on outcomes from the patient’s perspective. Because they reported improvement in HRQoL, despite a high complication rate, their findings allow clinicians to more confidently counsel patients about the potential impacts of the surgery [9]. Patients will expect that there may be future unplanned reoperations but that their quality of life should still be improved.
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