身高与高血压的关系:一项回顾性研究

SPG biomed Pub Date : 2022-07-25 DOI:10.3390/biomed2030024
Y. Shimizu, Hidenobu Hayakawa, Nagisa Sasaki, Midori Takada, T. Okada, M. Kiyama
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引用次数: 5

摘要

据报道,中年开始的身高下降是心血管疾病死亡的独立危险因素。最近的研究表明身高与高血压呈负相关,但高血压对身高下降的影响尚不清楚。由于高血压是一种确定的心血管危险因素,阐明基线高血压和身高下降之间的关系可能会成为估计死亡风险的有效工具。对11154名年龄在40-74岁之间的日本人进行了回顾性研究。身高损失被定义为年身高下降幅度最大的五分位数(男性≥2.015 mm/年,男性≥1.756 mm/年)。基线身高与男性高血压发病率呈显著负相关。身高每增加1个标准差(男性5.9 cm,女性5.6 cm),高血压发生率的调整优势比(OR)和95%置信区间(CI)分别为男性0.90(0.84,0.97)和女性1.07(0.91,1.26)。我们还发现,基线高血压与男性身高下降独立正相关。调整后的OR为男性1.25(1.11,1.42),女性0.93(0.71,1.21)。这些结果可能会导致一种有效的工具来估计身高下降的风险,据报道,身高下降与成人较高的死亡率风险有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Association between Height and Hypertension: A Retrospective Study
Height loss starting in middle age is reported to be an independent risk factor for cardiovascular mortality. Recent studies have revealed an inverse association between height and hypertension, but the influence of hypertension on height loss is unknown. Since hypertension is an established cardiovascular risk factor, clarifying the association between baseline hypertension and height loss could lead to an efficient tool to estimate the risk of mortality. A retrospective study of 11,154 Japanese aged 40–74 years was conducted. Height loss was defined as being in the highest quintile of annual height decrease (≥2.015 mm/year for men and ≥1.756 mm/year). Baseline height was significantly inversely associated with incident hypertension for men only. The adjusted odds ratio (OR) and 95% confidence interval (CI) for incident hypertension for each 1 standard deviation increment of height (5.9 cm for men and 5.6 cm for women) was 0.90 (0.84, 0.97) for men and 1.07 (0.91, 1.26) for women, respectively. We also found that baseline hypertension is independently positively associated with height loss for men only. The adjusted OR was 1.25 (1.11, 1.42) for men and 0.93 (0.71, 1.21) for women. These results might lead to an efficient tool for estimating the risk of height loss, which has been reported to be associated with a higher risk of mortality in adults.
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