The effect of drug information service using leaflet media and medication reminder chart on adherence and blood pressure of hypertensive patients in primary health care

Abstract Background: Treatment adherence is an important factor affecting blood pressure control in hypertensive patients. Intervention in pharmacy service can improve medication adherence and lower blood pressure. Objective: This study aimed to evaluate the effect of drug information service using leaflets and MRC on the level of patient compliance and lowering blood pressure. Method: The research design was a quasi-experimental pre-and post-design with control, the intervention group (n=20), and the control group (n=20). The patient adherence was measured using the MGLS questionnaire at the beginning and the end of the study. The intervention was performed by distributing a drug information leaflet and medication reminder chart (MRC). The differences of adherence pre and post-intervention were analyzed using paired t-test, while the differences in adherence and blood pressure between the control and the intervention group were analyzed using the Mann-Whitney test. Results: The results showed that there was a significant difference in adherence between pre and post-intervention (p<0.001). A significant difference was also found in the level of adherence between the control group and the intervention group (p<0.001). Whereas the decrease of systolic (p=0.396) and diastolic (p=0.564) blood pressure in the intervention group and control group was not different significantly. Conclusion: Drug information services using leaflets and MRCs affected patient adherence to medication, but did not interfere with the decrease of systolic and diastolic blood pressure. Keywords: leaflets, medication reminder chart, adherence, blood pressure