根据低磁场效应评估前列腺SABR的剂量分布

Pub Date : 2019-03-31 DOI:10.14407/JRPR.2019.44.1.26
J. Son, H. An, C. Choi, E. Chie, J. Kim, Jong Min Park, Jung In Kim
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引用次数: 3

摘要

背景:对比分析前列腺癌立体定向消融放疗(SABR)方案,探讨低磁场效应(0.35 T)对剂量分布的影响,并根据低磁场不同的剂量学参数。材料与方法:研究了20例使用MR-IGRT系统(ViewRay)接受5次36.25 Gy放射治疗的患者。规划靶体积(PTV),点平均剂量(Dmean)、最大剂量(Dmax)、最小剂量(Dmin)和接受总剂量100% (V100%)、95% (V95%)和90% (V90%)的体积。对于高危器官(OARs),使用直肠Dmax、V50%、V80%、V90%和V100%的差异;膀胱的Dmax、V50%、V30Gy、V100%;左右股骨头的V30Gy。对于靠近皮肤的外壳和内壳,比较Dmean、Dmin和Dmax。结果与讨论:在PTV分析中,低磁场下V100%、V95%、V90%的体积最大差异为0.54±0.63%。对于OAR,由于磁场较低,剂量分布无显著差异。在壳的结果中,虽然没有明显的剂量分布差异,但外壳的平均剂量分布差异为1.28±1.08 Gy,为Dmax。结论:在前列腺癌的PTV和OARs中,有磁场和无磁场计算的计划无统计学差异。然而,我们证实,当施加磁场时,人体外壳附近的剂量分布显著增加。
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Assessment of Dose Distributions According to Low Magnetic Field Effect for Prostate SABR
Background: Stereotactic ablative radiotherapy (SABR) plans in prostate cancer are compared and analyzed to investigate the low magnetic effect (0.35 T) on the dose distribution, with various dosimetric parameters according to low magnetic field. Materials and Methods: Twenty patients who received a 36.25 Gy in five fractions using the MR-IGRT system (ViewRay) were studied. For planning target volume (PTV), the point mean dose (Dmean), maximum dose (Dmax), minimum dose (Dmin) and volumes receiving 100% (V100%), 95% (V95%), and 90% (V90%) of the total dose. For organs-at-risk (OARs), the differences compared using Dmax, V50%, V80%, V90%, and V100% of the rectum; Dmax, V50%, V30Gy, V100% of the bladder; and V30Gy of both left and right femoral heads. For both the outer and inner shells near the skin, Dmean, Dmin, and Dmax were compared. Results and Discussion: In PTV analysis, the maximum difference in volumes (V100%, V95%, and V90%) according to low magnetic field was 0.54 ± 0.63% in V100%. For OAR, there was no significant difference of dose distribution on account of the low magnetic field. In results of the shells, although there were no noticeable differences in dose distribution, the average difference of dose distribution for the outer shell was 1.28 ± 1.08 Gy for Dmax. Conclusion: In the PTV and OARs for prostate cancer, there are no statistically-significant differences between the plan calculated with and without a magnetic field. However, we confirm that the dose distribution significantly increases near the body shell when a magnetic field is applied.
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