转移性睾丸癌合并口腔鳞状细胞癌并发消化道出血1例报告

M. Ashour, Sundus Nasim, Hallas Kadhim, Maan Faraj, Sylvia E Eshak
{"title":"转移性睾丸癌合并口腔鳞状细胞癌并发消化道出血1例报告","authors":"M. Ashour, Sundus Nasim, Hallas Kadhim, Maan Faraj, Sylvia E Eshak","doi":"10.53785/2769-2779.1112","DOIUrl":null,"url":null,"abstract":"Testicular cancer is a curable oncologic disease of males mostly aged 15-44 years. Most of the patients are successfully treated with radical orchiectomy. However, a delayed presentation may lead to a dismal prognosis. There are several risk factors including cryptorchidism, a first-degree relative with testicular cancer, hypospadias, childhood inguinal hernia, and military pollutant exposure, among others. The distant metastasis of testicular carcinoma to the lung, liver, and brain are widely described. We present a unique case of a 28-year-old male who presented with gastrointestinal (GI) bleeding. Later, it was discovered that he had a metastatic testicular carcinoma synchronous with an oral squamous cell carcinoma. Metastasis was detected by imaging including X-ray, computerized tomography (CT) of the chest, abdomen, and brain magnetic resonance imaging (MRI). The presence of two primary cancers concurrently is rare and indicates a poor prognosis. Because of the absence of risk factors in this patient, he was thought to be potentially exposed to depleted uranium from warfare due to his residence in Iraq. Markedly raised beta-human chorionic gonadotropin (b-HCG) titers indicate a possible nonseminomatous type; however, the exact type is unknown as the patient declined fine needle aspiration (FNA)/biopsy and orchiectomy. This case focuses on the atypical presentation and the importance of when to seek medical attention, as a delayed presentation can lead to a poor prognosis. Moreover, it heightens awareness that other malignancies may occur concurrently. As well as to emphasize on means that can be used to educate high-risk groups.","PeriodicalId":7266,"journal":{"name":"Advances in Clinical Medical Research and Healthcare Delivery","volume":"9 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Metastatic Testicular Cancer Patient with Synchronous Oral Squamous Cell Carcinoma Presented with Gastrointestinal Bleeding: A Case Report\",\"authors\":\"M. Ashour, Sundus Nasim, Hallas Kadhim, Maan Faraj, Sylvia E Eshak\",\"doi\":\"10.53785/2769-2779.1112\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Testicular cancer is a curable oncologic disease of males mostly aged 15-44 years. Most of the patients are successfully treated with radical orchiectomy. However, a delayed presentation may lead to a dismal prognosis. There are several risk factors including cryptorchidism, a first-degree relative with testicular cancer, hypospadias, childhood inguinal hernia, and military pollutant exposure, among others. The distant metastasis of testicular carcinoma to the lung, liver, and brain are widely described. We present a unique case of a 28-year-old male who presented with gastrointestinal (GI) bleeding. Later, it was discovered that he had a metastatic testicular carcinoma synchronous with an oral squamous cell carcinoma. Metastasis was detected by imaging including X-ray, computerized tomography (CT) of the chest, abdomen, and brain magnetic resonance imaging (MRI). The presence of two primary cancers concurrently is rare and indicates a poor prognosis. Because of the absence of risk factors in this patient, he was thought to be potentially exposed to depleted uranium from warfare due to his residence in Iraq. Markedly raised beta-human chorionic gonadotropin (b-HCG) titers indicate a possible nonseminomatous type; however, the exact type is unknown as the patient declined fine needle aspiration (FNA)/biopsy and orchiectomy. This case focuses on the atypical presentation and the importance of when to seek medical attention, as a delayed presentation can lead to a poor prognosis. Moreover, it heightens awareness that other malignancies may occur concurrently. As well as to emphasize on means that can be used to educate high-risk groups.\",\"PeriodicalId\":7266,\"journal\":{\"name\":\"Advances in Clinical Medical Research and Healthcare Delivery\",\"volume\":\"9 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-12-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in Clinical Medical Research and Healthcare Delivery\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.53785/2769-2779.1112\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Clinical Medical Research and Healthcare Delivery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.53785/2769-2779.1112","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

睾丸癌是一种可治愈的肿瘤疾病,多见于15-44岁的男性。大多数患者都成功地接受了根治性睾丸切除术。然而,延迟的表现可能导致预后不佳。有几个危险因素包括隐睾、有睾丸癌的一级亲属、尿道下裂、儿童腹股沟疝和接触军用污染物等。睾丸癌的远端转移到肺、肝和脑被广泛描述。我们提出一个独特的情况下,一个28岁的男性谁提出了胃肠道(GI)出血。后来,发现他患有转移性睾丸癌,同时伴有口腔鳞状细胞癌。影像学检查包括x线、胸部、腹部计算机断层扫描(CT)和脑磁共振成像(MRI)。同时出现两种原发癌症是罕见的,预示预后不良。由于这名病人没有危险因素,他被认为由于居住在伊拉克而可能受到战争中贫化铀的暴露。β -人绒毛膜促性腺激素(b-HCG)滴度明显升高提示可能为非半细胞瘤型;然而,由于患者拒绝细针穿刺/活检和睾丸切除术,确切类型尚不清楚。本病例着重于非典型表现和何时就医的重要性,因为延迟表现可能导致预后不良。此外,它提高了对其他恶性肿瘤可能同时发生的认识。同时强调可以用来教育高危人群的手段。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Metastatic Testicular Cancer Patient with Synchronous Oral Squamous Cell Carcinoma Presented with Gastrointestinal Bleeding: A Case Report
Testicular cancer is a curable oncologic disease of males mostly aged 15-44 years. Most of the patients are successfully treated with radical orchiectomy. However, a delayed presentation may lead to a dismal prognosis. There are several risk factors including cryptorchidism, a first-degree relative with testicular cancer, hypospadias, childhood inguinal hernia, and military pollutant exposure, among others. The distant metastasis of testicular carcinoma to the lung, liver, and brain are widely described. We present a unique case of a 28-year-old male who presented with gastrointestinal (GI) bleeding. Later, it was discovered that he had a metastatic testicular carcinoma synchronous with an oral squamous cell carcinoma. Metastasis was detected by imaging including X-ray, computerized tomography (CT) of the chest, abdomen, and brain magnetic resonance imaging (MRI). The presence of two primary cancers concurrently is rare and indicates a poor prognosis. Because of the absence of risk factors in this patient, he was thought to be potentially exposed to depleted uranium from warfare due to his residence in Iraq. Markedly raised beta-human chorionic gonadotropin (b-HCG) titers indicate a possible nonseminomatous type; however, the exact type is unknown as the patient declined fine needle aspiration (FNA)/biopsy and orchiectomy. This case focuses on the atypical presentation and the importance of when to seek medical attention, as a delayed presentation can lead to a poor prognosis. Moreover, it heightens awareness that other malignancies may occur concurrently. As well as to emphasize on means that can be used to educate high-risk groups.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信