新诊断的阻塞性睡眠呼吸暂停综合征患者甲状腺功能减退的患病率:一项前瞻性横断面研究

IF 0.2 Q4 RESPIRATORY SYSTEM
Lucy El-Maboud Suliman, Raed El Metwally Ali, Magda Ahmed, Maged Aboelazm
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引用次数: 0

摘要

OSAS最常见的表现之一是白天嗜睡,这也见于甲状腺功能减退症患者。我们假设甲状腺功能减退是OSAS发生的因素之一;因此,甲状腺功能减退症的适当管理可以简单地帮助减轻OSAS症状。研究目的:本研究的目的是评估本地区OSAS患者甲状腺功能减退的患病率,并比较伴有甲状腺功能减退的OSAS患者与无甲状腺功能减退的OSAS患者的呼吸多导睡眠图参数。患者和方法:在一项描述性前瞻性横断面研究中,我们的患者在曼苏拉大学医院胸内科睡眠呼吸障碍科睡眠呼吸障碍门诊就诊。所有患者都进行了完整的病史调查,包括睡眠问卷、肺部疾患、体格检查、人体测量、诊断性PSG、实验室评估(血清TSH和游离T4水平)、胸部x线和超声心动图。结果:OSAS患者分为两组(甲状腺功能减退和甲状腺功能正常)。12%的患者有明显的甲状腺功能减退,根据AHI分类,13、15、60的甲亢患者分别有轻度、中度、重度OSAS。轻度OSAS 2例,中度OSAS 1例,重度OSAS 9例。甲状腺功能减退组Epworth嗜睡量表得分显著高于正常组,平均得分为18±4.8分,正常组平均得分为12.47±6分(P = 0.003)。两组间PSG参数差异无统计学意义。AHI与血清TSH、T4水平呈正相关,但P值不显著。结论:甲状腺功能减退被认为是睡眠呼吸障碍发生的关键因素之一。在12%的OSAS患者中表现明显;然而,除了白天嗜睡的影响外,OSAS伴甲状腺功能减退组与甲状腺功能正常组的PSG参数差异不显著。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of hypothyroidism in newly diagnosed patients with obstructive sleep apnea syndrome: a prospective cross-sectional study
Introduction: One of the most common presentations of OSAS is daytime sleepiness, which is also seen in patients with hypothyroidism. We hypothesized that hypothyroidism is one of contributing factors in the development of OSAS; thus, adequate management of hypothyroidism can simply help to alleviate OSAS symptoms. Aim of the Study: The aim of this study was to evaluate the prevalence of hypothyroidism in OSAS patients in our locality and to compare respiratory polysomnographic parameters of OSAS patients with hypothyroidism versus those without hypothyroidism. Patients and Methods: In a descriptive prospective cross-sectional study, our patients attending Sleep Disordered Breathing Clinic at Sleep Disordered Breathing Unit, Chest Medicine Department, Mansoura University Hospital. All patients were subjected to full history taking with stress on sleep questionnaires, pulmonary complaints, physical examination, anthropometric measures, diagnostic PSG, laboratory evaluation (serum TSH and free T4 levels), and chest radiology and echocardiography. Results: There were two groups of OSAS participants (hypothyroid and euthyroid). Hypothyroidism was evident in 12% of patients;they were classified according to AHI, 13, 15, and 60 of Euthyroid patients had mild, moderate, and severe OSAS, respectively. hypothyroid patients, 2 mild OSAS, 1 moderate OSAS and 9 severe OSAS. Epworth sleepiness scale scores were significantly higher in the hypothyroid group with a mean score of 18 ± 4.8 vs 12.47 ± 6 in the euthyroid group (P = 0.003). Different PSG parameters showed no difference between the two groups. AHI, serum TSH level, and T4 levels were positively correlated but with insignificant P values. Conclusion: Hypothyroidism is thought to be one of the key players in the development of sleep-breathing disorders. It was evident in 12% of OSAS patients; however, the a proven insignificant difference in PSG parameters in OSAS with hypothyroidism versus euthyroid group, except for affection of daytime sleepiness.
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来源期刊
自引率
0.00%
发文量
46
审稿时长
22 weeks
期刊介绍: The journal will cover technical and clinical studies related to health, ethical and social issues in field of The Egyptian Journal of Chest Diseases and Tuberculosis aims to publish and inform readers and all chest physicians of the progress in medical research concerning all aspect of chest diseases. Publications include original articles review articles, editorials, case studies and reports which are relevant to chest diseases. The Journal also aims to highlight recent updates in chest medicine. . Articles with clinical interest and implications will be given preference.
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