评估印度南部三级转诊中心COVID-19妊娠的疾病结局:一项单中心回顾性队列研究

Q4 Medicine

Journal of SAFOG Pub Date : 2021-03-23 DOI:10.5005/JP-JOURNALS-10006-1822

Sabnam S. Nambiar, S. Ajith, V. Reshmi

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引用次数: 7

摘要

目的:探讨covid -19阳性妊娠的结局。材料与方法:回顾性收集我院2020年4月至9月收治的新冠肺炎阳性孕妇资料并进行分析。结果:30岁以下占78.85%，多胎占60.57%，37周以上占53.71%。76.85%无合并症，73.42%无旅行/接触史。84.57%无症状，2例发生严重急性呼吸道感染(SARI)，需重症监护。74.57%采用逆转录聚合酶链反应(RT-PCR)诊断。91.42%在6-10天内转为阴性。急性呼吸道感染患者需要重症监护病房(ICU)治疗，1例死亡。81.42%在入院8天至14天内出院，足月返回分娩。83.42%的患者无需药物治疗。96.28%的调查报告正常。83.14%的患者出院，16.57%的患者需要紧急产科干预。剖宫产率52.28%，既往剖宫产最常见指征(43.16%)。两个婴儿死产。99.20%， 5分钟后Apgar bb70。两人需要复苏。9例需要新生儿重症监护病房(NICU)住院。227个婴儿与母亲隔离，其中4个呈阳性。44人与母亲同住，30人转为阳性。167名母乳喂养，包括34名阳性婴儿。受影响的婴儿无症状。结论:COVID-19在妊娠期病程较轻，可能是由于免疫状态改变所致。然而，严重的病例可迅速恶化。有证据表明存在社区传播。COVID-19似乎增加了剖宫产率。在阴道分娩、同寝和母乳喂养后，新生儿传播率更高。临床意义:尽管进行了大量研究，但缺乏足够的数据来制定有关covid -19阳性妊娠的指南。我们希望我们的发现对正在进行的研究作出小小的补充，并进一步推动全球防治这一流行病的斗争。

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Assessing Disease Outcome in COVID-19 Pregnancies in a Tertiary Referral Center in South India: A Single-center Retrospective Cohort Study

Ab s t r Ac t Aim: To study the outcome in COVID-19-positive pregnancies. Materials and methods: Data collected and analyzed retrospectively from COVID-19-positive pregnant women admitted to our hospital between April and September 2020. Results: 78.85% of women below 30 years of age, 60.57% multigravidae, 53.71% above 37 weeks of gestation. 76.85% no comorbidities, 73.42% no history of travel/contact with COVID-19 cases. 84.57% asymptomatic, two had a severe acute respiratory infection (SARI), requiring intensive care. 74.57% diagnosed using reverse transcriptase-polymerase chain reaction (RT-PCR). 91.42% turned negative within 6–10 days. The SARI patients required intensive care unit (ICU) care, one expired. 81.42% discharged between 8 days and 14 days of admission, returned for delivery at term. 83.42% required no medication. 96.28% had normal investigation reports. 83.14% of patients discharged, 16.57% required emergency obstetric intervention. Cesarean section rate 52.28%, the previous cesarean section most common indication (43.16%). Two babies were stillborn. 99.20%, Apgar > 7 at 5 minutes. Two required resuscitations. Nine required neonatal intensive care unit (NICU) admission. Two hundred and seven babies isolated from their mother, four turned positive. Forty-four were roomed in with mothers, 30 turned positive. One hundred and sixty-seven were breastfed, included 34 positive babies. Affected babies were asymptomatic. Conclusion: COVID-19 runs a milder course in pregnancy, possibly due to altered immune status. However, severe cases can deteriorate rapidly. There is evidence of community spread. COVID-19 seemed to increase cesarean rates. Neonatal transmission appeared higher following vaginal deliveries, rooming-in, and breastfeeding. Clinical significance: There is a dearth of adequate data to formulate guidelines about COVID-19-positive pregnancies despite numerous studies. We hope that our findings make a humble addition to ongoing research and provide further impetus to the global fight against this pandemic.

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来源期刊

Journal of SAFOG Medicine-Obstetrics and Gynecology

CiteScore

0.40

自引率

0.00%

发文量

135

期刊介绍： Journal of South Asian Federation of Obstetrics and Gynaecology is the aim of this journal to provide platform for members to have access to scientific and peer-reviewed clinically oriented guidelines for practice and professional updating of subject of obstetrics and gynecology. The scope of South Asian Federation of Obstetrics and Gynaecology (SAFOG) journal is to cover the broad subject of obstetrics and gynecology and give out articles, information, and practice guidelines. The journal has fixed format of review articles, presentations as original studies by members and readers, operative skill reviews, case reports, and midwifery peer-reviewed practice guidelines. In addition, call upon experts and clinical authorities among member countries of SAFOG region to give out editorials on policy formulating topics such as maternal mortality, abortions, contraceptives, reproductive health preservation of women, etc. As well as to tabulate reproductive health country specific data to create awareness regarding the enormity of maternal and neonatal problems. To give out reader specific information for forthcoming professional events in the region. It remains a platform for better communication and exchange of reproductive indices among member countries. Also to amalgamate with world bodies, recommendations for practice guidelines for members. Brief of the journal: The SAFOG journal is the official organ and publication of South Asia Federation of Obstetrics and Gynecology. This is a scientific and peer-reviewed platform of exchange of professional activities, clinical practice guidelines, operative skill updates, and nursing midwifery practices among member countries.