{"title":"前列腺素的微生物转化","authors":"M. Miyano, C. Dorn, F. Colton, W. J. Marsheck","doi":"10.1039/C29710000425","DOIUrl":null,"url":null,"abstract":"(±)-Δ8(12)-15-Dehydro-PGE1(III), (±)-Δ8(12)-PGE1(IV), and (±)-15-epi-Δ8(12)-PGE1(V) have been synthesized from the readily available starting material (I), and compound (III) has been stereoselectively reduced by micro-organisms to either (+)- or (–)-(V).","PeriodicalId":17278,"journal":{"name":"Journal of The Chemical Society D: Chemical Communications","volume":"9 1","pages":"425-425"},"PeriodicalIF":0.0000,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"12","resultStr":"{\"title\":\"The microbial transformation of prostaglandins\",\"authors\":\"M. Miyano, C. Dorn, F. Colton, W. J. Marsheck\",\"doi\":\"10.1039/C29710000425\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"(±)-Δ8(12)-15-Dehydro-PGE1(III), (±)-Δ8(12)-PGE1(IV), and (±)-15-epi-Δ8(12)-PGE1(V) have been synthesized from the readily available starting material (I), and compound (III) has been stereoselectively reduced by micro-organisms to either (+)- or (–)-(V).\",\"PeriodicalId\":17278,\"journal\":{\"name\":\"Journal of The Chemical Society D: Chemical Communications\",\"volume\":\"9 1\",\"pages\":\"425-425\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1971-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"12\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of The Chemical Society D: Chemical Communications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1039/C29710000425\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of The Chemical Society D: Chemical Communications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1039/C29710000425","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
(±)-Δ8(12)-15-Dehydro-PGE1(III), (±)-Δ8(12)-PGE1(IV), and (±)-15-epi-Δ8(12)-PGE1(V) have been synthesized from the readily available starting material (I), and compound (III) has been stereoselectively reduced by micro-organisms to either (+)- or (–)-(V).
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