青少年皮肌炎:一种罕见疾病的常见表现

Mariana Capela, J. Reis, D. Soares, Andreia Ribeiro, I. Pais, Lúcia Rodrigues
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引用次数: 0

摘要

青少年皮肌炎是一种自身免疫性全身性血管病变,主要表现为横纹肌和皮肤的慢性炎症。作者报告的情况下,15岁的男孩提出了四个月的历史肌痛和近端肌肉无力的上肢和下肢。这些症状与日光状眼睑疹、手背红斑、Gottron丘疹、大腿伸肌面红斑和点疹以及轻度固体吞咽困难有关。血液检查显示肌肉酶增加,肌电图显示提示严重急性肌病的变化。开始静脉注射甲基强的松龙,随后是强的松龙和甲氨蝶呤的联合治疗方案。进行性吞咽困难,皮肤异常,肌肉力量改善。在这个病例中,作者打算提高人们对一种罕见疾病的认识,这种疾病基本上是临床诊断,在大多数病例中都有应该被认识到的特征性表现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Juvenile dermatomyositis: common manifestations of a rare disease
Juvenile dermatomyositis is an autoimmune systemic vasculopathy, mainly characterized by chronic inflammation of the striated muscle and skin. The authors report the case of a 15-year-old boy presenting with a four-month history of myalgia and proximal muscle weakness on the upper and lower limbs. These symptoms were associated with heliotrope palpebral exanthema, erythema in the dorsum of the hands, Gottron’s papules, erythematous and petechial rash on the extensor face of the thighs, and mild dysphagia for solids. Blood tests revealed an increase in muscle enzymes and electromyography showed changes suggestive of severe acute myopathy. Intravenous methylprednisolone was initiated, followed by a combination regimen of prednisolone and methotrexate. Progressive dysphagia, cutaneous abnormality, and muscular strength improvement were noted. With this case, the authors intend to raise awareness of a rare disease with an essentially clinical diagnosis, presenting in most cases with characteristic manifestations that should be recognised.
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