儿童脑膜炎球菌败血症的骨科后果

T. Edwards, L. Bowen, F. Bintcliffe, J. Aird, F. Monsell
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引用次数: 5

摘要

本研究的目的是使用确定的脑膜炎球菌败血症患者人群来计算骨科并发症的发生率。回顾性分析2001年1月1日至2012年12月31日布里斯托尔皇家儿童医院儿科重症监护病房(PICU)收治的所有脑膜炎球菌败血症患者的医疗记录和x线片。在出院时存活的130例脑膜炎球菌败血症患者中,10例出现骨科后遗症,总发病率为7.7%。9例患者需要截肢,以下肢为主,16/22(72.7%)。8例患者中发现48例生长板异常。39(81.3%)最常见的是胫骨远端(38.5%)。10个踝关节被确定为内翻错位。使用明确定义的分母,本研究确定脑膜炎球菌败血症后骨科后遗症的发生率为7.7%。国家临床卓越研究所(NICE)建议生长障碍的发生率约为3%。这项研究强调了对脑膜炎球菌败血症后骨科并发症的低估。应考虑对高危患者进行密切随访,以减少这些使人衰弱的损伤的潜在影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
THE ORTHOPAEDIC CONSEQUENCES OF CHILDHOOD MENINGOCOCCAL SEPTICAEMIA
The aim of this study is to use a defined population of patients with meningococcal septicaemia to calculate the incidence of orthopaedic complications. Medical records and radiographs were analyzed retrospectively for all patients admitted to the Paediatric Intensive Care Unit (PICU) of the Bristol Royal Hospital for Children from 01/01/2001 to 31/12/2012 with meningococcal septicaemia. Of the 130 patients with meningococcal septicaemia alive at discharge, 10 developed orthopaedic sequelae, representing an overall incidence in this patient population of 7.7%. 9 patients required an amputation, mostly in the lower limb, 16/22 (72.7%). 48 growth plate abnormalities were identified in 8 patients. 39 (81.3%) The most commonly affected was the distal tibia (38.5%). 10 ankles were identified as having a varus malalignment. 6 patients had documented leg length discrepancy Using a clearly defined denominator this study has identified an incidence of orthopaedic sequelae following meningococcal septicaemia of 7.7%. The National Institute for Clinical Excellence (NICE) suggested that the incidence of growth disturbance is approximately 3%. This study highlights the underestimation of orthopaedic complications following meningococcal septicaemia. Close follow up of at risk patients should be considered to reduce the potential impact of these debilitating injuries.
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