Yang Wang, Han Liu, Jie Wu, Lu Zhao, Hanghang Zhang, Qianqian Sun, Andong Zhao, Hongfang Zhang, Bin Wang
{"title":"黄芩苷和京尼平苷联合应用对脑缺血恢复期大鼠小胶质细胞活化及5-脂氧合酶表达的影响","authors":"Yang Wang, Han Liu, Jie Wu, Lu Zhao, Hanghang Zhang, Qianqian Sun, Andong Zhao, Hongfang Zhang, Bin Wang","doi":"10.14218/fim.2022.00047","DOIUrl":null,"url":null,"abstract":"Background and objectives: This study aimed to analyze the effects of baicalin (BC) and geniposide (GP) in combination (7:3) on the activation of microglia (MG) and 5-lipoxygenase (5-LOX) expression in rats during the recovery period after cerebral ischemia and to determine whether inhibition of the 5-LOX pathway is beneficial for M1-to-M2 polarization of MG. Methods: Sprague Dawley rats were divided into five groups: control, model","PeriodicalId":73126,"journal":{"name":"Future integrative medicine","volume":"16 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Effects of Baicalin and Geniposide in Combination on Microglial Activation and 5-Lipoxygenase Expression in Rats during Recovery from Cerebral Ischemia\",\"authors\":\"Yang Wang, Han Liu, Jie Wu, Lu Zhao, Hanghang Zhang, Qianqian Sun, Andong Zhao, Hongfang Zhang, Bin Wang\",\"doi\":\"10.14218/fim.2022.00047\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background and objectives: This study aimed to analyze the effects of baicalin (BC) and geniposide (GP) in combination (7:3) on the activation of microglia (MG) and 5-lipoxygenase (5-LOX) expression in rats during the recovery period after cerebral ischemia and to determine whether inhibition of the 5-LOX pathway is beneficial for M1-to-M2 polarization of MG. Methods: Sprague Dawley rats were divided into five groups: control, model\",\"PeriodicalId\":73126,\"journal\":{\"name\":\"Future integrative medicine\",\"volume\":\"16 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-05-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Future integrative medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.14218/fim.2022.00047\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future integrative medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14218/fim.2022.00047","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The Effects of Baicalin and Geniposide in Combination on Microglial Activation and 5-Lipoxygenase Expression in Rats during Recovery from Cerebral Ischemia
Background and objectives: This study aimed to analyze the effects of baicalin (BC) and geniposide (GP) in combination (7:3) on the activation of microglia (MG) and 5-lipoxygenase (5-LOX) expression in rats during the recovery period after cerebral ischemia and to determine whether inhibition of the 5-LOX pathway is beneficial for M1-to-M2 polarization of MG. Methods: Sprague Dawley rats were divided into five groups: control, model
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
