动态冠脉路线图用于冠脉介入造影和缩短放疗时间(DRM-COR)

M. Maher, B. Zarif, A. Elgamal, Hatem Khairy, A. Magdy
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摘要

目的:血管造影中常用的造影剂对患者有一定的风险。这包括过敏、肾毒性和肺水肿。此外,辐射暴露与高度骨髓抑制、不孕症和其他危害有关。本研究的目的是比较动态路线图技术与常规造影剂在冠状动脉介入治疗中的辐射暴露、透视时间和造影剂肾病发生率。方法:40例患者随机分为两组,一组为病例组,另一组为对照组。病例组在他们的手术中使用DRM技术,对照组接受国家心脏研究所使用的标准对比。结果:两组患者在年龄、性别、高血压、糖尿病、吸烟、缺血性心脏病史等危险因素上无统计学差异。两组超声心动图结果无差异。干预第5天肌酐水平、造影剂用量和透视时间差异有统计学意义。DRM降低了造影剂体积,减少了辐射暴露,尽管没有减少透视或手术时间。这导致降低血清肌酐水平升高,成功率相似。建议:使用尽可能小的造影剂体积和辐射剂量始终是操作人员的目标。动态路线图技术被推荐用于所有冠状动脉介入治疗,特别是那些CIN合并CKD的高危患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dynamic Coronary Roadmap for Contrast, and Radiation Time Reduction during Coronary Intervention (DRM-COR)
Purpose: The regularly used contrast media in the angiography procedures and interventions are known to carry certain risks to the patient. This includes allergy, nephrotoxicity, and pulmonary edema. Additionally, radiation exposure is associated with high bone marrow depression, infertility, and other hazards. The purpose of the study was to compare the Dynamic Roadmap technology to the regular contrast used in coronary intervention regarding radiation exposure, fluoroscopy time, and incidence of Contrast Induced Nephropathy. Methodology: Observational prospective cohort with 2 arms where 40 patients were randomly divided into 2 arms a case and control groups. The case group had DRM technology used in their procedures where the control group received the standard contrast used in the National Heart Institute. Findings: Findings showed no statistically significant difference between the 2 groups in age, sex, and risk profile including status of Hypertension, Diabetes Mellitus, Smoking and history of Ischemic Heart Disease. There was no difference in echocardiographic findings of both groups. There was significant difference in creatinine level at the 5th day of intervention and volume of contrast used and fluoroscopy time. DRM reduced contrast volume, reduced radiation exposure despite not reducing fluoroscopy or procedure time. This resulted in reduction of elevation in serum creatinine levels with similar success rates. Recommendations: Using the least possible contrast volume and radiation doses should always be target of the operator. Dynamic roadmap technology is recommended in all coronary interventions specially those at high risk of CIN with CKD.
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