尼日利亚卡拉巴大学教学医院角膜溃疡的十年回顾

A. Ibanga, B. Etim, D. Nkanga, U. Asana, R. Duke
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引用次数: 1

摘要

目的:回顾2003年1月至2012年12月期间卡拉巴大学教学医院(UCTH)角膜溃疡的模式、趋势、易感因素、特征和视力结果,以期提供更高质量的患者管理。研究设计:回顾性。学习地点和时间:2003年1月至2012年12月,眼科。方法:对卡拉巴尔大学教学医院眼科诊断为角膜溃疡并接受治疗的患者的医疗记录进行回顾。结果:2003 - 2012年就诊于眼科的角膜溃疡患者158例,可检索到的病例仅101例。其中化脓性溃疡69例(68%),莫伦氏溃疡5例(5%),病毒性溃疡10例(10%),盾性溃疡1例(1%),不明原因溃疡16例(16%)。大多数角膜溃疡患者(56例,77.78%)根据世界卫生组织分类为失明,出院时仍有49例(68.05%)失明。差异无统计学意义(p值0.26)。在研究期间,单侧表现最为常见66(95.65%)。受影响最大的年龄组是4160岁。化脓性角膜溃疡更为常见(42,60.87%)。中国生物医学工程学报,14(4):1-10,2016;文章no.BMRJ。男性25168例。以农民为主(20.28.99%),学生为主(13.18.84%)。外伤(农业)(34例,49.28%)是化脓性角膜溃疡最常见的诱发因素,而植物性/农业相关物质是最常见的诱发因素。另一个原因是有害传统药物(HTEM)(5.7.25%)。大量患者(52例,75.36%)在入院前接受过某种形式的治疗,包括使用许可药物和/或HTEM(68例,98.55%)。很少有患者(18例,26.09%)进行了微生物学评估。分离到的微生物有曲霉属(18.26.09%)和金黄色葡萄球菌(3.4.35%)。结论:在尼日利亚这样的发展中国家,化脓性角膜溃疡仍然是角膜溃疡的一个重要原因,可能造成毁灭性的视力损害,并给公共卫生系统造成巨大损失。大规模的公共教育规划和加强现有卫生系统以加强包括康复在内的管理,将在防治角膜疾病的斗争中大有帮助
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Corneal Ulcers at the University of Calabar Teaching Hospital in Nigeria - A Ten Year Review
Aim: To review the pattern, trend, predisposing factors, characteristics and visual outcome of corneal ulcers at the University of Calabar Teaching Hospital (UCTH) between January 2003 and December 2012 with a view to providing improved quality patient management. Study Design: Retrospective. Place and Duration of Study: Department of Ophthalmology from January 2003 to December 2012. Methodology: A review of medical records of patients diagnosed with corneal ulcers and treated in the Ophthalmology Department of the University of Calabar Teaching Hospital, Calabar. Results: One hundred and fifty-eight (158) patients with corneal ulcer visited the Department of Ophthalmology from 2003 to 2012 but only one hundred and one (101) patient records could be retrieved. Of this number, 69(68%) were suppurative ulcer, 5(5%) Mooren’s ulcer, 10(10%) viral, 1(1%) shield ulcer while 16(16%) of the cases were indeterminate. Most patients with corneal ulcer (56, 77.78%) were classified as blind according to the World Health Organisation and at discharge 49 individuals (68.05%) remained blind. This difference was not statistically significant (p-value 0.26). Unilateral presentation was most common 66 (95.65%) during the study period. The age group mostly affected was 4160years. Suppurative corneal ulcer was more common (42, 60.87%) Original Research Article Ibanga et al.; BMRJ, 14(4): 1-10, 2016; Article no.BMRJ.25168 2 among male patients. The majority (20, 28.99%) of the people were farmers while (13, 18.84%) were students. Trauma (agricultural) (34, 49.28%) was the most common predisposing factor in suppurative corneal ulcer with vegetative/agricultural related materials as the most frequent causative agent. Another cause was harmful traditional medication (HTEM) (5, 7.25%). A significant number of patients (52, 75.36%) would have received some form of treatment prior to presentation at the hospital and this included use of licensed drugs and/or HTEM (68, 98.55%). Very few patients (18, 26.09%) had microbiological assessment. Organisms isolated were aspergillus species (18, 26.09%) and Staphylococcus aureus (3, 4.35%). Conclusion: Suppurative corneal ulcer remains a significant cause of corneal ulcer in a developing country like Nigeria with potentially devastating visual impairment and significant cost to the public health system. Massive public education programmes and strengthening of existing health systems to enhance its management including rehabilitation will go a long way in the fight against corneal
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