几种体外测定法评价樟叶油的抗氧化活性

O. Eldahshan, Gina Zakaria, Nada A. Mostafa, Rania F Abou El-Ezz
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引用次数: 1

摘要

肉桂属的许多物种因其多种健康益处而被用于传统医学。近年来,肉桂的一个重要特性是它的抗氧化活性。许多已知的肉桂品种已经被评估了它们的抗氧化性能,并显示出令人惊讶的积极结果,这促使人们进一步研究正在研究的物种的潜在抗氧化作用。肉桂被归类为营养保健品,这是所研究植物的理想特性。在本研究中,樟叶挥发油(Cinnamomum glandulliferum;采用Clevenger仪器对樟科植物Nees进行分离,并进行GC/MS分析,对其成分进行化学谱分析。结果表明,桉叶油中主要含有桉叶油脑、sabinene和α -松油醇。我们的研究旨在通过三种被广泛认可的抗氧化方法来检测肉桂的抗氧化活性:DPPH法(以trolox为标准),FRAP法(以抗坏血酸为标准),ORAC法(以槲皮素为标准)。结果表明,作为一种潜在的治疗或预防氧化应激相关疾病和障碍的药物,它可能是一个有希望进一步研究的候选者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of Antioxidant Activity of Cinnamomum glanduliferum Leaf Oil Using Several In-vitro Assays
Numerous species of the genus Cinnamomum have been utilized in traditional medicine for their diverse range of health benefits. One of the key properties of cinnamon that has gained significant attention in recent years is its antioxidant activity. Numerous well-known cinnamon species have been assessed for their antioxidant properties and have exhibited surprisingly positive results, which have prompted further investigation into the potential antioxidant effects of the species under study that have yet to be studied. Cinnamon is classified as a nutraceutical which is a desirable characteristic in the studied plant. In the current study, the essential oil of the leaf of Cinnamomum glanduliferum (Wall.) Nees (Lauraceae) was isolated using the Clevenger apparatus and was subjected to GC/MS analysis, enabling the chemical profiling of its constituents. Results revealed that cineole, sabinene, and α -terpineol were identified as the prominent compounds in the oil. Our study aimed at examining the antioxidant activity of Cinnamomum glanduliferum through the utilization of three widely recognized antioxidant assays: DPPH assay by comparing IC 50 values of oil with trolox as a standard, FRAP assay by comparing ferrous equivalents of oil with that of ascorbic acid, and ORAC assay by comparing IC 50 values of oil with quercetin. The results suggest that it may be a promising candidate for further investigation as a potential therapeutic or preventative agent against oxidative stress-related diseases and disorders.
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