某三级教学医院甲状腺恶性肿瘤的临床病理特点及治疗结果的回顾性研究

S. Iyengar
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引用次数: 1

摘要

简介:甲状腺癌在发展中国家发病率很高,在过去十年中几乎翻了一番。这主要是由于提高了对结节性疾病的认识、筛查和诊断。甲状腺癌有明显的性别倾向,女性的发病率是男性的三倍,在女性中排名第八。目的:分析甲状腺癌患者的临床病理特点,评价治疗模式和长期治疗效果。材料与方法:本研究回顾性分析所有甲状腺癌病例,包括所有经组织病理学证实的甲状腺癌病例。采用IBM SPSS version 21进行统计分析。结果:共纳入67例患者,平均年龄44.72±14.99岁。研究人群中女性占68.66%,男性占31.34%,61人(91.05%)有不同大小的颈部肿胀及其他相关表现。甲状腺功能检查显示,91.04%(61例)的患者甲状腺功能正常,40.3%(27例)的患者行甲状腺全切除术,95.52%(64例)的患者生存良好。结论:本研究证实乳头状癌是分化型甲状腺癌中最常见的形式(70.6%)。远处转移的发生率为4.48%,最常见于肺部。这种疾病在女性中比在男性中更为普遍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Retrospective Study of Clinicopathological Profile and Treatment Outcomes of Thyroid Malignancies Presented to a Tertiary Care Teaching Hospital
Introduction: Thyroid cancer is on the developing world over – almost doubling in the past ten years. This is mainly due to improved awareness, screening and diagnosis of the nodular disease. Thyroid cancer has an apparent gender predisposition with women being affected three times more than men and 8th most mostly occurring cancer among women. To analyze the clinicopathological profile of thyroid cancer patients and to assess the pattern of treatment and long-term treatment outcomes. Material and methods: The current study was retrospective case record review of all the thyroid cancer cases including all the histopathological confirmed cases of thyroid cancer. The statistical analysis was carried out by using IBM SPSS version 21. Results: A total of 67 subjects were included with a mean age of 44.72 ± 14.99 years. Females were 68.66% and males 31.34% of the study population, 61 (91.05%) people had usual presentation of neck swelling of various sizes and other associated findings. Thyroid function test showed that 91.04% (61) showed euthyroid status, 40.3% (27) had a total thyroidectomy, 95.52% (64) of the patients were alive and well. Conclusion: The study bears evidence to the fact that papillary carcinoma is the most commonly occurring form of differentiated thyroid cancer (70.6%). The prevalence of distant metastasis is 4.48% and most commonly found in the lung. The disease is more prevalent among women than men.
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