脊柱结核和神经功能缺损:印度中部农村三级保健中心的10年研究

R. Patil, G. Mote, A. Wankhede, K. Wandile, C. Badole
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引用次数: 0

摘要

背景:印度是世界上27%结核病病例的发源地。相比之下,肺外结核(EPTB)病例的发病率低于肺结核(PTB),但EPTB的发病率没有显著降低。脊柱结核是最常见的骨骼结核。目的:我们的目的是研究和确定脊柱结核的临床放射学特征和神经系统受累的发生率以及与之相关的因素。背景和设计:这是一项在印度中部三级保健中心进行的回顾性研究。研究对象和方法:共纳入114例脊柱结核患者。数据回顾性收集自2008年1月至2018年12月,使用图片存档和医院图片存档和通信系统。研究了x线片、磁共振成像扫描、计算机断层扫描和超声检查结果。对病史和临床检查结果进行全面分析。使用统计分析:数据分析使用Epi Info软件。结果:男性74例(64.9%),女性40例(35.1%)。农村85例(74.5%)高于城市29例(24.5%)。经神经学评估,52例(45.6%)出现截瘫/截瘫,2例(1.7%)出现四肢瘫痪。感觉障碍10例(10.5%)。5例(4.4%)出现肠/膀胱受累。大多数神经缺损病例累及背椎体30(61.1%)。结论:脊柱结核类型多样,诊断困难。我们观察到高比例的病例有神经功能障碍。其中大多数为迟发性结核病。这突出了早期诊断和彻底治疗在脊柱结核的治疗中非常重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Spinal tuberculosis and neurological deficit: A 10-year study in rural tertiary care center of central India
Background: India is a home for 27% of the world's tuberculosis (TB) cases. When compared, extrapulmonary TB (EPTB) cases have a lower incidence than pulmonary TB (PTB), but there is no significant reduction in the incidence of EPTB than PTB. Spinal TB is most common of skeletal TB. Aims: We aimed to study and to identify the clinical-radiological features in spinal TB and the incidence of neurological involvement along with factors associated with it. Settings and Design: This was a retrospective study in a tertiary care center of Central India. Subjects and Methods: A total of 114 cases with spinal TB were included in the study. Data collected retrospectively from January 2008 to December 2018 using a picture archiving and picture archiving and communication system of the hospital. Radiographs, magnetic resonance imaging scan, computed tomography, and ultrasound findings were studied. History and clinical examination findings were thoroughly analyzed. Statistical Analysis Used: Data were analyzed using Epi Info Software. Results: There were 74 (64.9%) male cases and 40 (35.1%) female cases. Most of the cases belong to rural 85 (74.5%) than urban 29 (24.5%) area. After neurological evaluation, paraparesis/paraplegia was observed in 52 (45.6%) cases and tetraplegia in 2 (1.7%) cases. Sensory deficit was observed in 10 (10.5%) cases. Bowel/bladder involvement was present in 5 (4.4% cases). Most of the cases with neurodeficit had dorsal vertebral involvement 30 (61.1%). Conclusions: The pattern of spinal TB is varied and is difficult to get diagnosed. We observed a high proportion of cases with neurodeficit. Most of them were with late-onset TB. This highlights that early diagnosis and complete treatment are very important in the treatment of TB of the spine.
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